Sicor Ltd. v. Cetus Corp.

51 F.3d 848, 26 U.C.C. Rep. Serv. 2d (West) 686, 95 Cal. Daily Op. Serv. 2392, 95 Daily Journal DAR 4180, 1995 U.S. App. LEXIS 6614, 1995 Trade Cas. (CCH) 70,945, 1995 WL 142410
CourtCourt of Appeals for the Ninth Circuit
DecidedApril 3, 1995
DocketNo. 93-15667
StatusPublished
Cited by110 cases

This text of 51 F.3d 848 (Sicor Ltd. v. Cetus Corp.) is published on Counsel Stack Legal Research, covering Court of Appeals for the Ninth Circuit primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Sicor Ltd. v. Cetus Corp., 51 F.3d 848, 26 U.C.C. Rep. Serv. 2d (West) 686, 95 Cal. Daily Op. Serv. 2392, 95 Daily Journal DAR 4180, 1995 U.S. App. LEXIS 6614, 1995 Trade Cas. (CCH) 70,945, 1995 WL 142410 (9th Cir. 1995).

Opinion

LEAVY, Circuit Judge:

Two foreign corporations filed the instant action in federal district court against several foreign and domestic companies, asserting federal antitrust claims and state law causes of action for breach of contract, interference with contractual relations, and indebitatus assumpsit. The district court entered summary judgment in favor of the defendants on all claims, and the plaintiffs have appealed. We affirm in part, reverse in part, and remand.

FACTS AND PRIOR PROCEEDINGS

Doxorubicin hydrochloride (“doxorubicin”) is a chemical used in the treatment of some fourteen different types of cancer. Although it is one of the most effective and widely sold anti-cancer drugs available in the United States, it is also highly toxic in bulk form and must be specially prepared and packaged, or “finished,” before it can be marketed in dosage form. Consequently, a distributor of [851]*851bulk doxorubicin must obtain approval from the Food and Drug Administration (“FDA”) of the distributor’s source (i.e., the manufacturer of the bulk doxorubicin) before turning it over to a finisher.

Erbamont N.V., a Netherlands Antilles company, once enjoyed a virtual monopoly on the sale of doxorubicin in the United States through its Italian subsidiary, Farmitalia' Carlo Erba, S.r.l. (“Farmitalia”). Farmitalia, which had developed the techniques necessary to produce doxorubicin in commercial quantities-, held an American patent on the drug’s production until June 1988, as well as related patents on certain other production techniques until April 1991. Farmitalia marketed doxorubicin in the United States under the label Adriamyein exclusively through Er-bamont N.V.’s wholly owned American subsidiary, Erbamont, Inc., and its Adria division (collectively, “Erbamont”).

Shortly before the expiration of Farmita-lia’s product patent, another Italian firm, Si-cor S.p.A., decided to enter the American market by manufacturing generic doxorubi-cin under an arrangement with its wholly owned United Kingdom subsidiary, Sicor Limited, which owned the microorganism from which doxorubicin is produced. As neither Sicor S.p.A. nor Sicor Limited (jointly, “Sicor”) had an American presence or sales network, Sicor entered into a distribution agreement with Aleo Chemicals, Ltd. (“Aleo”), a U.K. corporation, and a finishing agreement with Cetus-Ben Venue Therapeutics (“CBVT”),1 a California partnership, in late 1987.

On February 1, 1988, Aleo and CBVT executed a distribution agreement, dated as of November 5, 1987 (“Distribution Agreement”), in which Aleo appointed CBVT to act as its exclusive American distributor of Sicor-manufactured doxorubicin to be finished by CBVT under the provisions of Sicor’s contract with CBVT (“Supply Agreement”). In exchange for this exclusive arrangement, CBVT was to pay Aleo $1,000,000 and distribution fees equal to 50% of CBVT’s revenues from the sale of finished doxorubicin, net of CBVT’s expenses in buying bulk doxorubicin under the Supply Agreement and various taxes, rebates, and other charges.

Farmitalia and Erbamont (“Farmitalia Group”) responded immediately to this challenge to their dominant position in the United States market. In 1988, Erbamont unsuccessfully sought an injunction from the United States International Trade Commission (“ITC”) against CBVT’s importation of SI-COR-manufactured doxorubicin on the ground of patent infringement. Shortly thereafter, CBVT filed an antitrust and unfair competition action against the Farmitalia Group in federal district court.

Meanwhile, Aleo and CBVT amended the Distribution Agreement on April 10, 1989 (“First Amendment”). Among other things, the First Amendment modified the terms governing CBVT’s payment of distribution fees to Aleo and established a reimbursement account to fund CBVT’s pursuit of antitrust claims against the Farmitalia Group. That same day, Sicor and CBVT entered into a superseding agreement, retroactively dated November 5, 1987 (“Second Supply Agreement”), separating Sicor’s supply obligations from Alco’s distribution commitments under the Distribution Agreement.2 By letter agreement dated October 8, 1990 (“Second Amendment”), Aleo and CBVT further amended the Distribution Agreement to permit CBVT to deduct from distribution fees owed to Aleo 50% of CBVT’s costs in pursu[852]*852ing its legal claims against the Farmitalia Group.

On May 25, 1989, CBVT made its first American sale pursuant to the Second Supply Agreement, thereby starting the running of the contract’s three-year term. Between June 1989 and September 1990, CBVT made substantial inroads into Erbamont’s dominant position in the American doxorubicin market. By underpricing its main competitor on sales of doxorubicin in both powder and solution form, CBVT increased its market share from 0% to 80%. During this same time period, two smaller competitors held a combined market share of approximately 9%. Erbamont’s market share declined correspondingly.

The Farmitalia Group did not ignore this competition. In addition to the failed ITC claim, Farmitalia initiated legal proceedings in Italy against Sicor, alleging theft of a proprietary microorganism essential to the production of doxorubicin. Although the action was eventually dismissed, Farmitalia obtained a temporary injunction against Sicor S.p.A.’s doxorubicin production facility in Milan on July 21, 1989. The plant remained closed until March 1990, when it reopened temporarily. On September 21, 1990, the plant was again shut down pursuant to an Italian court’s sequestration decree. The plant has remained closed since then.

In response to the production halt at its plant in Italy, Sicor notified CBVT and sought to obtain supplies of bulk doxorubicin from other firms to meet its interim needs. On October 9, 1990, CBVT and Sicor met with Pharmaehemie, B.V., a European distributor of Sicor-manufactured doxorubicin. Pharmaehemie offered CBVT 2.4 kilograms of FDA-approved, Sicor-produced bulk doxo-rubicin. CBVT declined the offer, explaining that its inventory of Sicor-produced bulk dox-orubicin would last until the following summer.

Meanwhile, Sicor and CBVT modified their supply arrangement by agreement dated October 8, 1990 (“Letter Agreement”).3 The Letter Agreement revised the pricing formula for CBVT’s purchases of doxorubicin and extended from 60 to 180 days the payment period for Sicor’s invoices to CBVT. In addition, the Letter Agreement required CBVT to remit to Sicor 50% of its proceeds, net of various discounts and rebates, from sales of doxorubicin in the United States. Also pursuant to the Letter Agreement, the parties confirmed and ratified the remainder of the Second Supply Agreement.

In the meantime, Sicor sought an alternate producer to perform its contractual supply obligations. This search led to Mercian Corporation (“Mercian”), a Japanese company with prior FDA approval as a producer of bulk doxorubicin and an ongoing relationship with Sicor. Before Mercian could fill CBVT’s orders from Sicor, however, CBVT would be required to obtain FDA approval as a finisher of Mercian-manufactured bulk dox-, orubicin, an administrative process with an expected time length the parties dispute: CBVT contended that FDA approval would take up to eighteen months, while Sicor estimated no more than five months. Accordingly, in late 1990, Sicor and Mercian began negotiating an agreement allowing Mercian to supply bulk doxorubicin in Sicor’s stead under the terms of the Second Supply Agreement.4

Free access — add to your briefcase to read the full text and ask questions with AI

Related

Haynes v. Uponor, Inc.
N.D. California, 2022
(PC) Martin v. Her
E.D. California, 2021
(PC) Rodriguez v. Baughman
E.D. California, 2020
William Terryberry v. Liberty Mutual Fire Ins. Co.
688 F. App'x 489 (Ninth Circuit, 2017)
Lennar Mare Island, LLC v. Steadfast Insurance
176 F. Supp. 3d 949 (E.D. California, 2016)
Burgoon v. Narconon of Northern California
125 F. Supp. 3d 974 (N.D. California, 2015)
Ukiru v. Federal Home Loan Mortgage Corp.
602 F. App'x 395 (Ninth Circuit, 2015)
Creditors Comm Adamson Apparel v. Arnold Simon
785 F.3d 1285 (Ninth Circuit, 2015)
Orchard Supply Hardware LLC v. Home Depot USA, Inc.
939 F. Supp. 2d 1002 (N.D. California, 2013)
A-J Marine, Inc. v. Corfu Contractors, Inc.
810 F. Supp. 2d 168 (District of Columbia, 2011)
McCoy v. Department of Army
789 F. Supp. 2d 1221 (E.D. California, 2011)
Adoma v. UNIVERSITY OF PHOENIX, INC.
779 F. Supp. 2d 1126 (E.D. California, 2011)

Cite This Page — Counsel Stack

Bluebook (online)
51 F.3d 848, 26 U.C.C. Rep. Serv. 2d (West) 686, 95 Cal. Daily Op. Serv. 2392, 95 Daily Journal DAR 4180, 1995 U.S. App. LEXIS 6614, 1995 Trade Cas. (CCH) 70,945, 1995 WL 142410, Counsel Stack Legal Research, https://law.counselstack.com/opinion/sicor-ltd-v-cetus-corp-ca9-1995.