Trustees of University of Pennsylvania v. St. Jude Children's Research Hospital

940 F. Supp. 2d 233, 2013 WL 1499518, 2013 U.S. Dist. LEXIS 52750
CourtDistrict Court, E.D. Pennsylvania
DecidedApril 12, 2013
DocketCivil Action No. 12-4122
StatusPublished
Cited by12 cases

This text of 940 F. Supp. 2d 233 (Trustees of University of Pennsylvania v. St. Jude Children's Research Hospital) is published on Counsel Stack Legal Research, covering District Court, E.D. Pennsylvania primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

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Trustees of University of Pennsylvania v. St. Jude Children's Research Hospital, 940 F. Supp. 2d 233, 2013 WL 1499518, 2013 U.S. Dist. LEXIS 52750 (E.D. Pa. 2013).

Opinion

MEMORANDUM

DALZELL, District Judge.

I. Introduction

We consider here a motion by St. Jude Children’s Research Hospital (“St. Jude”) to dismiss Count I of the complaint filed by the Trustees of the University of Pennsylvania (“Penn” or “the University”), a Count which alleges tortious interference [235]*235with contractual relations.1 St. Jude argues first that the claim is barred by the Noert'-Pennington doctrine, and that, if it is not, the University has failed to state a claim on which relief can be granted.

a. Factual History

This action between the University and St. Jude concerns two Materials Transfer Agreements (“MTAs” or “Agreements”) between the parties, one executed in 2003 and the other in 2007.

The Agreements arose out of research that doctors at each institution had been conducting on immunotherapy cancer treatment. The University avers that Carl H. June, M.D., a Professor of Pathology and Laboratory Medicine at Penn, had developed a “CD19 ScFv DNA lentiviral construct” (the “June Construct”) that “causes T cells to express chimeric antigen receptors (CARs) in patients such that their cancer is treated”. Am. Comp. ¶ 8.

According to the University’s amended complaint, Dario Campana, M.D., Ph.D., a doctor at St. Jude2, had also developed “an anti-CD19 BB-£ chimeric receptor construct” (the “Campana Construct”). Id. at ¶ 11. St. Jude claims that this construct is a molecule that “can be expressed on the surface of a normal human immune T-cell, and ... causes the T-cell to recognize and attack certain leukemic cancer cells”. MTD at 3. Dr. June and Dr. Campana met at a conference in 2003, after which Dr. June asked Dr. Campana to provide him with a sample of the Campana Construct. Am. Comp. ¶ 12.

In order to facilitate this exchange, the parties entered into the first MTA at issue here on December 17, 2003. Id. at ¶ 13. That Agreement defined the “Material” St. Jude was transferring as “the anti-CD19BB-£ chimeric T-cell receptor construct, including any progeny, portions, unmodified derivatives and any accompanying know-how or data”. 2003 MTA at ¶ 1, Am. Comp. Ex. D. The Agreement provided that “the Material will only be used to create a lentiviral chimeric T-cell receptor construct to be used in pre-clinical studies”, id. at ¶ 3, and “may not be used in humans” or “for any commercial purpose.” Id. at ¶ 4. It further provided that the University would “not commercialize any product that contains Material without the prior written approval of St. Jude.” Id. at ¶ 8.-

By 2007, Dr. June wished to use the June Construct to conduct human clinical trials, Am. Comp. ¶ 17, and so in February 2008, the parties executed a second MTA, dated October 2, 20073, allowing the product to be used in such clinical trials. 2007 MTA at ¶ 3, Am. Comp. Ex. E. That agreement contained the same definition of “Material” as found in the 2003 agreement. Id. at ¶ 1.

In August 2011, Dr. June described the results of his study in an article in The New England Journal of Medicine, New Eng. J. Med. 8:725-733 (2011) and in Sci[236]*236ence Translational Medicine, 2011; 3(95):95ra73. Id. ¶ 23. St. Jude, in a complaint we will discuss below, avers that the University did not submit the Science Translational Medicine article to it for approval and that Penn and Dr. June failed to acknowledge that the Material the article referred to had come from St. Jude. St. Jude Comp. ¶ 49.

In a November 22, 2011 letter, the University informed St. Jude that it wished to terminate the MTA4. Am. Comp. Ex. F.

The University contends that it “contractually agreed to exclusively negotiate with Novartis regarding a ground-breaking collaboration that would develop Dr. June’s cellular immunotherapy for general cancer patient use.” Id. ¶ 27. According to the amended complaint, “The University ... actively negotiated with Novartis a collaboration under which the University would receive funding that would allow it to continue with clinical trials of the Penn Immunotherapy without undue delay”, and “[a]s of July 10, 2012, the University and Novartis had made substantial progress towards reaching an agreement that would allow continued development of the Penn Immunotherapy Technology.” Id. ¶¶ 28-29.

According to the University’s complaint, “[smarting in August 2011, St. Jude and the University had ongoing discussions regarding St. Jude’s contention that the University allegedly breached the 2003 and 2007 MTAs.” Id. ¶30. St. Jude claims that by January of 2012 it “had learned that the University had breached both the 2003 MTA and the 2007 MTA by publishing experimental results without the required acknowledgment of St. Jude and without sharing the proposed publication with St. Jude beforehand”, and by “engaging in prohibited commercialization efforts”, MTD at 5.

As a result, St. Jude’s General Counsel, Clinton Hermes, and outside counsel, Glenn Krinsky, spoke to University General Counsel Wendy White by telephone on January 20, 2012. Id. While they were speaking, Krinsky sent White an e-mail, explaining:

Mr. Hermes and I telephoned you several minutes ago to inform you that St. Jude intended to file suit today against the Trustees of the University of Pennsylvania (“Penn”) in connection with disputes arising under that certain Collaboration and Materials Transfer Agreement ... As an alternative to filing suit, Mr. Hermes offered Penn the opportunity to enter into a “Stand Still Agreement” with St. Jude to enable the parties to discuss the disputes arising under the MTAs with the hopes of resolving those disputes and obviating the need for a lawsuit ... In exchange ... you have agreed on behalf of Penn that Penn will not file a lawsuit or initiate any other type of judicial or administrative proceeding ... until no earlier than Friday February 3rd, 2012. On behalf of Penn, you explicitly acknowledge that there are no restrictions on St. Jude’s ability to initiate legal proceedings related to the MTAs including, but not limited to, a federal court lawsuit against Penn in the Western District of Tennessee at any time after 3:00pm EST on Tuesday January 31, 2012 in the event that Penn has not executed a Stand Still Agreement ...

[237]*237Id. at 5-6. According to St. Jude, White responded that she “Understood and confirmed” the terms of the e-mail, and when the deadline for settlement passed, the parties had not reached an agreement. Id. at 6.

b. Procedural History

On July 11, 2012, St. Jude filed a breach of contract action against the University in the Western District of Tennessee. See St. Jude Comp., MTD Ex. A-l. St. Jude sought eight forms of preliminary and permanent injunctive relief: (1) specific performance of the 2003 and 2007 MTAs and to instruct the University to make submissions to journals crediting Dr. Campana and St. Jude’s with the use of chimeric antigen receptors (“CAR”), St. Jude Comp, at ¶ 85(l)-(4), and (2) an order that (a) the University enter into a Joint Materials Transfer Agreement covering the distribution of materials that contain the CAR, (b) the University not enter into an agreement to commercialize any product containing the CAR without St.

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940 F. Supp. 2d 233, 2013 WL 1499518, 2013 U.S. Dist. LEXIS 52750, Counsel Stack Legal Research, https://law.counselstack.com/opinion/trustees-of-university-of-pennsylvania-v-st-jude-childrens-research-paed-2013.