Silbersher v. Allergan plc

District Court, N.D. California·Decided March 20, 2023·No. 3:18-cv-03018·Unknown

Opinion

1 2 3 4 UNITED STATES DISTRICT COURT 5 NORTHERN DISTRICT OF CALIFORNIA 6 ZACHARY SILBERSHER, et al., 7 Case No. 18-cv-03018-JCS Plaintiffs, 8 v. AMENDED ORDER GRANTING 9 MOTIONS TO DISMISS ALLERGAN INC., et al., 10 Re: Dkt. Nos. 186, 187 Defendants. 11

12 13 I. INTRODUCTION 14 This action was brought under the federal False Claims Act (“FCA”), 31 U.S.C. §§ 3729- 15 3733, and various state laws, by Plaintiff-Relator Zachary Silbersher (“Relator”) on behalf of the 16 United States and numerous States (the “States”)1 against two sets of defendants: 1) the “Allergan 17 Defendants” or “Allergan”2; and 2) the “Adamas Defendants” or “Adamas.”3 Each set of 18 defendants brings a motion to dismiss (hereinafter, the “Allergan Motion” and the “Adamas 19 Motion” and collectively, the “Original Source Motions”). The Court vacated the motion hearing 20 set for March 17, 2023 at 9:30 a.m. pursuant to Civil Local Rule 7-1(b) and issued an Order 21 granting the Original Source Motions on March 13, 2017. It has not yet entered judgment in this 22 case. 23

24 1 Relator brings this action on behalf of California, Colorado, Connecticut, Delaware, the District of Columbia, Florida, Georgia, Hawaii, Illinois, Indiana, Iowa, Louisiana, Maryland, 25 Massachusetts, Michigan, Minnesota, Montana, Nevada, New Jersey, New Mexico, New York, North Carolina, Oklahoma, Rhode Island, Tennessee, Texas, Vermont, Virginia, and Washington. 26 2 The Allergan Defendants are: Allergan, Inc., Allergan USA, Inc., Allergan Sales, LLC, and Forest Laboratories Holdings, Ltd. For purposes of this motion, the term “Allergan Defendants” 27 does not include Defendant Allergan PLC, which has been dismissed from this action, even 1 At the March 17, 2023 case management conference, it became apparent that the parties 2 disagree about the implications of the Court’s March 13, 2023 Order with respect to the Relator’s 3 state law claims. These claims were not addressed in any of the parties’ briefs in connection with 4 the Original Source Motions. The Court issues this Amended Order to clarify that in granting the 5 Original Source Motions, it decides only the challenges to the Relator’s federal law claims and 6 does not decide whether his state law claims are barred. See Amarel v. Cornell, 102 F.3d 1494, 7 1515 (9th Cir.1996) (“[T]he interlocutory orders and rulings made pre-trial by a district judge are 8 subject to modification by the district judge at any time prior to final judgment”). Other than this 9 Introduction section and the Conclusion section, the Amended Order is identical to the March 13, 10 2023 Order.4 11 II. BACKGROUND 12 A. First Amended Complaint5 13 The operative complaint in this action is the First Amended Complaint (“FAC”). In the 14 FAC, Relator alleges that the Adamas and Allergan Defendants misled the United States Patent 15 Office (“Patent Office”) into issuing invalid patents protecting the drugs Namenda XR® and 16 Namzaric®, thus perpetuating their monopoly power and allowing them to overcharge the federal 17 government and the States for these drugs under various programs, including Medicare and 18 Medicaid. FAC ¶¶ 1-8. 19 Relator is a citizen of the State of New York whose “profession focuses on investigating 20 invalid pharmaceutical patents that brand manufacturers use to protect their drugs from price 21 competition.” Id. ¶ 9. He alleges that he has “[t]hrough his independent investigation . . . 22 uncovered non-public information supporting the claims set forth” in the FAC. Id. He further 23 alleges that his “independent research and investigation has generated information that is 24 independent of, and materially adds to, any publicly-disclosed allegations and transactions.” Id. 25

26 4 The parties have consented to the jurisdiction of the undersigned magistrate judge pursuant to 28 U.S.C. § 636(c). 27 5 This section is taken verbatim from the Court’s December 11, 2020 Order on Defendants’ 1 According to Relator, he is an “original source” of information within the meaning of the FCA and 2 he provided the information on which his claims are based to the States and the federal 3 government before he initiated this action. Id. ¶ 10. 4 Relator alleges that Allergan, Inc., Allergan USA, Inc., Allergan Sales, LLC, and Forest 5 Laboratories Holdings, Ltd. are subsidiaries or divisions of Allergan PLC, which was called 6 Activas PLC until June 15, 2015. Id. ¶ 17. Activas PLC acquired Forest Laboratories, Inc. on 7 July 1, 2014 and acquired Allergan, Inc. on March 17, 2015. Id. ¶¶ 17, 49. Relator alleges that 8 “Defendant Forest Laboratories Holdings, Ltd. is an Irish corporation with its principal place of 9 business at Cumberland House, 1 Victoria Street, Hamilton HMU, Bermuda” and that “Allergan is 10 the successor-in-interest to Forest Laboratories, LLC (f/k/a Forest Laboratories, Inc.) and is liable 11 for any damages to which Forest is liable.” Id. ¶ 16.6 12 Defendant Adamas Pharma, LLC is a Delaware limited liability company with its 13 principal place of business in Emeryville, California; Defendant Adamas Pharmaceuticals, Inc. is 14 a Delaware corporation, also based in Emeryville, California. Id. ¶¶ 18-19. According to Relator, 15 in 2012, Adamas Pharmaceuticals, Inc. entered into a commercialization and development 16 agreement with Forest Laboratories, Inc. with respect to memantine hydrochloride (“memantine”) 17 drugs. Id. ¶¶ 50, 59. Relator alleges that “[a]s part of that agreement, Adamas . . . granted Forest 18 an exclusive license to all of the Went Patents[,]” discussed below. Id. 19 Namenda XR® is a delayed-release drug whose active pharmaceutical ingredient (“API”) 20 is memantine. Id. ¶ 50. It is used to treat patients with dementia related to Alzheimer’s disease. 21 Id. According to Relator, generics of Namenda XR® first became available on February 21, 2018, 22 after the Federal Circuit invalidated patents asserted by Defendants in connection with that drug. 23 Id. Relator alleges that Allergan’s United States net revenue for Namenda XR® was 24 approximately $452.8 million in 2017, $627.6 million in 2016 and $759.3 million in 2015. Id. ¶ 25 52. 26

27 6 As noted above, the FAC defines “Allergan” as including Allergan, Inc., Allergan USA, Inc., 1 Namzaric® is also a delayed-release drug prescribed to treat patients with dementia related 2 to Alzheimer’s disease. Id. ¶ 53. It has two APls: memantine hydrochloride and donepezil 3 hydrochloride. Id. ¶ 54. Relator alleges that “[g]eneric manufacturers have been ready to enter 4 the market since at least July 13, 2015, but they have been prevented from doing so by the 5 fraudulently-obtained patents asserted by Defendants” and that “[t]o date, no generic manufacturer 6 has entered the market for Namzaric®.” According to Relator, Allergan launched Namzaric® on 7 May 18, 2015; its net revenue for Namzaric® was approximately $130.8 million in 2017, $57.5 8 million in 2016 and $11.2 [million] in 2015.” Id. ¶ 56. 9 Relator alleges that “Defendants listed three categories of patents for Namenda XR® and 10 Namzaric® in the [Food and Drug Administration (“FDA”)]’s database of “Approved Drug 11 Products with Therapeutic Equivalence Evaluations,” commonly known as the “Orange Book[, ]” 12 thereby preventing generic manufacturer’s from entering the market. FAC ¶ 57. 13 The first category of patents is the Went Patents, a group of eleven patents that list Dr. 14 Gregory T. Went, PhD., the founder and CEO of Adamas, as the first inventor.7 Id. ¶ 58. For 15 Namenda XR®, six of the Went Patents are listed in the Orange Book (the ’209, ’708, ’379, ’752, 16 ’085, and ’233 patents), while all eleven are listed for Namzaric®. Id.

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