Silbersher v. Allergan plc

CourtDistrict Court, N.D. California
DecidedMarch 13, 2023
Docket3:18-cv-03018
StatusUnknown

This text of Silbersher v. Allergan plc (Silbersher v. Allergan plc) is published on Counsel Stack Legal Research, covering District Court, N.D. California primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Silbersher v. Allergan plc, (N.D. Cal. 2023).

Opinion

1 2 3 4 UNITED STATES DISTRICT COURT 5 NORTHERN DISTRICT OF CALIFORNIA 6 ZACHARY SILBERSHER, et al., 7 Case No. 18-cv-03018-JCS Plaintiffs, 8 v. ORDER GRANTING MOTIONS TO 9 DISMISS ALLERGAN INC., et al., 10 Re: Dkt. Nos. 186, 187 Defendants. 11

12 13 I. INTRODUCTION 14 This action was brought under the federal False Claims Act (“FCA”), 31 U.S.C. §§ 3729- 15 3733, by Plaintiff-Relator Zachary Silbersher (“Relator”) on behalf of the United States and 16 numerous States (the “States”)1 against two sets of defendants: 1) the “Allergan Defendants” or 17 “Allergan”2; and 2) the “Adamas Defendants” or “Adamas.”3 Each set of defendants brings a 18 motion to dismiss (hereinafter, the “Allergan Motion” and the “Adamas Motion” and collectively, 19 the “Motions”). The Court finds that the Motions are suitable for determination without a hearing 20 and therefore vacates the motion hearing set for March 17, 2023 at 9:30 a.m. pursuant to Civil 21 Local Rule 7-1(b). The Case Management Conference set for the same date will be moved 22 from 9:30 a.m. to 2:00 p.m. For the reasons stated below, the Motions are GRANTED.4 23 1 Relator brings this action on behalf of California, Colorado, Connecticut, Delaware, the District 24 of Columbia, Florida, Georgia, Hawaii, Illinois, Indiana, Iowa, Louisiana, Maryland, Massachusetts, Michigan, Minnesota, Montana, Nevada, New Jersey, New Mexico, New York, 25 North Carolina, Oklahoma, Rhode Island, Tennessee, Texas, Vermont, Virginia, and Washington. 2 The Allergan Defendants are: Allergan, Inc., Allergan USA, Inc., Allergan Sales, LLC, and 26 Forest Laboratories Holdings, Ltd. For purposes of this motion, the term “Allergan Defendants” does not include Defendant Allergan PLC, which has been dismissed from this action, even 27 though references to “Allergan” in the operative complaint include Allergan PLC. 1 II. BACKGROUND 2 A. First Amended Complaint5 3 The operative complaint in this action is the First Amended Complaint (“FAC”). In the 4 FAC, Relator alleges that the Adamas and Allergan Defendants misled the United States Patent 5 Office (“Patent Office”) into issuing invalid patents protecting the drugs Namenda XR® and 6 Namzaric®, thus perpetuating their monopoly power and allowing them to overcharge the federal 7 government and the States for these drugs under various programs, including Medicare and 8 Medicaid. FAC ¶¶ 1-8. 9 Relator is a citizen of the State of New York whose “profession focuses on investigating 10 invalid pharmaceutical patents that brand manufacturers use to protect their drugs from price 11 competition.” Id. ¶ 9. He alleges that he has “[t]hrough his independent investigation . . . 12 uncovered non-public information supporting the claims set forth” in the FAC. Id. He further 13 alleges that his “independent research and investigation has generated information that is 14 independent of, and materially adds to, any publicly-disclosed allegations and transactions.” Id. 15 According to Relator, he is an “original source” of information within the meaning of the FCA and 16 he provided the information on which his claims are based to the States and the federal 17 government before he initiated this action. Id. ¶ 10. 18 Relator alleges that Allergan, Inc., Allergan USA, Inc., Allergan Sales, LLC, and Forest 19 Laboratories Holdings, Ltd. are subsidiaries or divisions of Allergan PLC, which was called 20 Activas PLC until June 15, 2015. Id. ¶ 17. Activas PLC acquired Forest Laboratories, Inc. on 21 July 1, 2014 and acquired Allergan, Inc. on March 17, 2015. Id. ¶¶ 17, 49. Relator alleges that 22 “Defendant Forest Laboratories Holdings, Ltd. is an Irish corporation with its principal place of 23 business at Cumberland House, 1 Victoria Street, Hamilton HMU, Bermuda” and that “Allergan is 24 the successor-in-interest to Forest Laboratories, LLC (f/k/a Forest Laboratories, Inc.) and is liable 25 26 U.S.C. § 636(c). 27 5 This section is taken verbatim from the Court’s December 11, 2020 Order on Defendants’ 1 for any damages to which Forest is liable.” Id. ¶ 16.6 2 Defendant Adamas Pharma, LLC is a Delaware limited liability company with its 3 principal place of business in Emeryville, California; Defendant Adamas Pharmaceuticals, Inc. is 4 a Delaware corporation, also based in Emeryville, California. Id. ¶¶ 18-19. According to Relator, 5 in 2012, Adamas Pharmaceuticals, Inc. entered into a commercialization and development 6 agreement with Forest Laboratories, Inc. with respect to memantine hydrochloride (“memantine”) 7 drugs. Id. ¶¶ 50, 59. Relator alleges that “[a]s part of that agreement, Adamas . . . granted Forest 8 an exclusive license to all of the Went Patents[,]” discussed below. Id. 9 Namenda XR® is a delayed-release drug whose active pharmaceutical ingredient (“API”) 10 is memantine. Id. ¶ 50. It is used to treat patients with dementia related to Alzheimer’s disease. 11 Id. According to Relator, generics of Namenda XR® first became available on February 21, 2018, 12 after the Federal Circuit invalidated patents asserted by Defendants in connection with that drug. 13 Id. Relator alleges that Allergan’s United States net revenue for Namenda XR® was 14 approximately $452.8 million in 2017, $627.6 million in 2016 and $759.3 million in 2015. Id. ¶ 15 52. 16 Namzaric® is also a delayed-release drug prescribed to treat patients with dementia related 17 to Alzheimer’s disease. Id. ¶ 53. It has two APls: memantine hydrochloride and donepezil 18 hydrochloride. Id. ¶ 54. Relator alleges that “[g]eneric manufacturers have been ready to enter 19 the market since at least July 13, 2015, but they have been prevented from doing so by the 20 fraudulently-obtained patents asserted by Defendants” and that “[t]o date, no generic manufacturer 21 has entered the market for Namzaric®.” According to Relator, Allergan launched Namzaric® on 22 May 18, 2015; its net revenue for Namzaric® was approximately $130.8 million in 2017, $57.5 23 million in 2016 and $11.2 [million] in 2015.” Id. ¶ 56. 24 Relator alleges that “Defendants listed three categories of patents for Namenda XR® and 25 Namzaric® in the [Food and Drug Administration (“FDA”)]’s database of “Approved Drug 26

27 6 As noted above, the FAC defines “Allergan” as including Allergan, Inc., Allergan USA, Inc., 1 Products with Therapeutic Equivalence Evaluations,” commonly known as the “Orange Book[, ]” 2 thereby preventing generic manufacturer’s from entering the market. FAC ¶ 57. 3 The first category of patents is the Went Patents, a group of eleven patents that list Dr. 4 Gregory T. Went, PhD., the founder and CEO of Adamas, as the first inventor.7 Id. ¶ 58. For 5 Namenda XR®, six of the Went Patents are listed in the Orange Book (the ’209, ’708, ’379, ’752, 6 ’085, and ’233 patents), while all eleven are listed for Namzaric®. Id. According to Relator, the 7 Went Patents “are all generally directed to an extended release formulation for 8 memantine.” Id. 9 The parent patent for all of the Went Patents is the ’291 patent, which was issued on 10 November 15, 2011. Id. ¶ 61. Relator alleges that on June 21, 2010, during prosecution of the 11 ’291 patent application, the Examiner issued an Office Action that rejected the pending claims as 12 anticipated. Id. ¶ 62. In response, on November 5, 2010, Dr. Went and his co-inventors amended 13 the independent claims of the ’291 patent application and submitted a declaration by Dr. Went 14 (the “Original Went Declaration” or “2010 Went Declaration”) in which he discussed the results 15 of two clinical studies conducted by Adamas, the C106 Study and the ME110 Study. Id. ¶ 63. 16 Relator alleges that Dr.

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Silbersher v. Allergan plc, Counsel Stack Legal Research, https://law.counselstack.com/opinion/silbersher-v-allergan-plc-cand-2023.