United States v. Jazz Pharmaceuticals PLC

CourtDistrict Court, D. Massachusetts
DecidedSeptember 23, 2025
Docket1:21-cv-10891
StatusUnknown

This text of United States v. Jazz Pharmaceuticals PLC (United States v. Jazz Pharmaceuticals PLC) is published on Counsel Stack Legal Research, covering District Court, D. Massachusetts primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
United States v. Jazz Pharmaceuticals PLC, (D. Mass. 2025).

Opinion

UNITED STATES DISTRICT COURT DISTRICT OF MASSACHUSETTS ___________________________________ ) UNITED STATES OF AMERICA, et al., ) ex rel. LEONARDO S. SORGI, ) ) Plaintiffs, ) ) v. ) Civil Action ) No. 21-cv-10891-PBS JAZZ PHARMACEUTICALS PLC, JAZZ ) PHARMACEUTICALS, INC., and JAZZ ) PHARMACEUTICALS IRELAND LIMITED, ) ) Defendants. ) ______________________________ )

MEMORANDUM AND ORDER September 23, 2025 Saris, J. INTRODUCTION In this qui tam action,1 Plaintiff-Relator Leonardo S. Sorgi (“Relator”) alleges that Defendants Jazz Pharmaceuticals plc, Jazz Pharmaceuticals, Inc., and Jazz Pharmaceuticals Ireland Limited (collectively, “Jazz” or “Defendants”) fraudulently obtained patents to unlawfully maintain a monopoly over Xyrem, a central nervous system (“CNS”) depressant. According to Relator, this

1 The amended complaint was brought on behalf of the United States, California, Colorado, Connecticut, Delaware, the District of Columbia, Florida, Georgia, Guam, Hawaii, Illinois, Indiana, Iowa, Louisiana, Massachusetts, Michigan, Minnesota, Montana, Nevada, New Jersey, New Mexico, New York, North Carolina, Oklahoma, Puerto Rico, Rhode Island, Tenneessee, Texas, Vermont, Virginia, the Virgin Islands, and Washington. See Dkt. 63. scheme excluded lower-cost generic competitors and caused Medicare and Medicaid to reimburse Xyrem prescriptions at inflated prices in violation of the False Claims Act (“FCA”), 31 U.S.C.

§ 3729(a)(1)(A) & (B). Jazz moves to dismiss the complaint under Federal Rule of Civil Procedure 12(b)(6), arguing that Relator cannot state a plausible claim on which relief can be granted for six independent reasons, including that Relator’s allegations were previously disclosed and are barred under the FCA’s public disclosure bar.2 After a hearing, the Court ALLOWS Jazz’s motion to dismiss (Dkt. 71). BACKGROUND

Because this FCA claim is predicated on a still-valid patent, a brief description of the patent process is necessary. The Court begins there and then describes the facts alleged in Relator’s complaint (Dkt. 63), which the Court accepts as true at this stage. See Artuso v. Vertex Pharms., Inc., 637 F.3d 1, 5 (1st Cir. 2011).

2 Jazz also argues that Relator’s complaint should be dismissed, either in full or in part, because: (i) Relator failed to plead with particularity a scheme by Jazz to defraud the government, including the who, what, when, where, and how of the alleged fraud; (ii) Relator failed to plead all the elements of an FCA violation; (iii) Relator’s state-law claims mirror the federal FCA claim and fail for the same reasons; (iv) the FCA’s qui tam provisions are unconstitutional; and (v) this Court lacks personal jurisdiction over Jazz Pharmaceuticals PLC and Jazz Pharmaceuticals Ireland Limited. I. Patent Prosecution and Inter Partes Review A person may apply and be entitled to a patent for an invention that is novel and non-obvious to a person having ordinary

skill in the art. See 35 U.S.C. §§ 102-103. To apply for a patent, an applicant must submit a specification and claims to the United States Patent and Trademark Office (“PTO”) in a process known as patent prosecution. Patent prosecution is an ex parte process completed without the participation of third parties. Without an adversary to challenge the applicant during patent prosecution, the applicant must abide by a duty of “candor, good faith, and honesty.” Molins PLC v. Textron, Inc., 48 F.3d 1172, 1178 (Fed. Cir. 1995). He must disclose to the PTO “all information known to [him] to be material to patentability.” 37 C.F.R. § 1.56(a). Once the PTO decides that the invention satisfies the statutory requirements, a patent is issued that grants the owner the

exclusive right to “make[], use[], offer[] to sell, or sell[]” the invention for a period of time. 35 U.S.C. § 271(a). After issuance, patents remain subject to challenge. One mechanism is inter partes review (“IPR”). “IPR is a trial-like, adversarial” proceeding conducted by the Patent Trial and Appeal Board (“PTAB”), an adjudicative body within the PTO. United States ex rel. Silbersher v. Valeant Pharms. Int’l, Inc., 89 F.4th 1154, 1160-61, 1165 (9th Cir.), cert. denied, 145 S. Ct. 140 (2024). IPR permits third parties to challenge patents on the grounds of lack of novelty or obviousness based on prior art patents and publications. See 35 U.S.C. §§ 102-03, 311(b). A challenger may not use IPR proceedings to allege that a patent was obtained

through intentional misconduct or fraud. See id. § 311(b). II. Facts Underpinning the Present Litigation A. The Parties Relator is a patent attorney who focuses on investigating pharmaceutical patents. He has never worked for Jazz. Jazz Pharmaceuticals plc, an Irish public limited company with principal executive offices located in Dublin, Ireland, is the parent company of the other two Defendants. Jazz Pharmaceuticals, Inc., a Delaware corporation with a principal place of business in Palo Alto, California, is the American distributor of Xyrem. Jazz Pharmaceuticals Ireland Limited, an Irish corporation with a principal place of business in Dublin, Ireland, is the owner of

the patents at issue in this case. Jazz manufactures, sells, and distributes Xyrem, a CNS depressant used to treat narcolepsy and cataplexy. Jazz has profited immensely from Xyrem, earning over $1.6 billion per year at its peak. B. Prosecution of the ‘306 Patent Family While its patent on Xyrem’s active ingredient -- sodium oxybate, the sodium salt of gamma-hydroxybutyrate (“GHB”) -- has long since expired, Jazz has continued to profit from Xyrem by obtaining patents on different applications of the medication. Currently, all of Jazz’s patents on Xyrem cover the coadministration of Xyrem with other CNS depressants, such as the medication valproate. U.S. Patent No. 8,772,306 (“the ‘306

patent”), which was the first patent to issue, covers a method of “orally administering . . . at least [a] 5% decrease in an effective dosage amount of the GHB or salt thereof when the patient is receiving a concomitant administration of valproate.” Dkt. 63 ¶ 55 (second alteration in original). In other words, the ‘306 patent covers any dose reduction of Xyrem between 5% and 99% when Xyrem and valproate are coadministered. The patents covering the coadministration of Xyrem with other CNS depressants are collectively referred to as “the ‘306 patent family.”3 The ‘306 patent issued from U.S. Patent Application No. 13/872,997 (“the ‘997 application”), which Jazz filed on April 29, 2013. On September 13, 2013, the PTO issued a Non-Final Office

Action rejecting the claims pending under the ‘997 application, explaining that prior art taught coadministration of GHB and other medications to treat sleep disorders. In response, Jazz argued that the prior art “d[id] not teach or suggest that valproate could be combined with GHB, or what might be the effects of the two if combined.” Id. ¶ 52. Jazz insisted that the safety and efficacy of

3 The other patents in the ‘306 patent family are U.S. Patent Nos. 9,050,302, 9,486,426, 10,213,400, 10,864,181, 11,253,494, and 11,986,446.

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United States v. Jazz Pharmaceuticals PLC, Counsel Stack Legal Research, https://law.counselstack.com/opinion/united-states-v-jazz-pharmaceuticals-plc-mad-2025.