Roofers Local No. 149 Pension Fund, on behalf of itself and all others similarly situated v. GSK PLC, et al.

CourtDistrict Court, E.D. Pennsylvania
DecidedMarch 4, 2026
Docket2:25-cv-00618
StatusUnknown

This text of Roofers Local No. 149 Pension Fund, on behalf of itself and all others similarly situated v. GSK PLC, et al. (Roofers Local No. 149 Pension Fund, on behalf of itself and all others similarly situated v. GSK PLC, et al.) is published on Counsel Stack Legal Research, covering District Court, E.D. Pennsylvania primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Roofers Local No. 149 Pension Fund, on behalf of itself and all others similarly situated v. GSK PLC, et al., (E.D. Pa. 2026).

Opinion

IN THE UNITED STATES DISTRICT COURT FOR THE EASTERN DISTRICT OF PENNSYLVANIA

ROOFERS LOCAL NO. 149 PENSION : FUND, on behalf of itself and all others : similarly situated, : CIVIL ACTION Plaintiff, : : v. : NO. 25-00618 : GSK PLC, et al., : Defendants. :

MEMORANDUM KENNEY, J. MARCH 4, 2026 Plaintiffs filed this securities fraud class action on February 4, 2025, alleging violations of Section 10(b) of the Exchange Act, Rule 10b-5, and Section 20(a) in connection with Defendants’ purported decades-long concealment of Zantac’s potential to form a carcinogenic substance. See ECF No. 1; see also ECF No. 25 (operative complaint). On September 5, 2025, Defendants moved to dismiss Plaintiffs’ Amended Complaint pursuant to Federal Rules of Civil Procedure 9(b) and 12(b)(6), and pursuant to the Private Securities Litigation Reform Act (“PSLRA”) (the “Defendants’ Motion”). See ECF No. 34. Plaintiffs oppose dismissal. See ECF No. 37. For the reasons set forth below, the Court will GRANT Defendants’ Motion (ECF No. 34) and DISMISS Plaintiffs’ Amended Complaint (ECF No. 25) WITH PREJUDICE. I. BACKGROUND A. Factual Background The Court draws the following allegations from Plaintiffs’ Amended Complaint and assumes them to be true at the motion-to-dismiss stage. See City of Cambridge Ret. Sys. v. Altisource Asset Mgmt. Corp., 908 F.3d 872, 878 (3d Cir. 2018). Defendant GlaxoSmithKline plc (“GSK”) is a global “pharmaceutical and biotechnology company” that has “business[] units spanning pharmaceuticals (including respiratory and HIV drugs), vaccines, and consumer healthcare.” ECF No. 25 ¶¶ 27, 40. One of GSK’s consumer products is Zantac, which used to be a widely used medication for the treatment of heartburn, acid reflux, and ulcers. Id. ¶¶ 3, 35. The active ingredient in Zantac is ranitidine. Id. ¶ 3. GSK and its predecessors developed Zantac in

1976 and began selling it in the United States in 1983 after gaining approval of the drug from the U.S. Food and Drug Administration (“FDA”). Id. ¶¶ 4, 28, 34–35. From 1983 until 2019, GSK made billions of dollars from its sales of Zantac. Id. ¶¶ 34, 37. In 2019, Valisure, an independent research laboratory, conducted tests on Zantac, which revealed that Zantac and generic ranitidine contained N-Nitrosodimethylamine (“NDMA”)—a carcinogenic substance—at levels “that were up to 26,000 times the FDA’s daily limit.” Id. ¶¶ 3, 6, 71–72 (emphasis omitted). Notably, studies have found that exposure to and consumption of NDMA can be associated with the development of various cancers. Id. ¶ 68. Valisure confidentially reported the results of its tests to the FDA, which also submitted them to the European Medicines Agency (“EMA”). Id. ¶¶ 6, 73. Thereafter, EMA sent an inquiry to GSK

requesting additional information about the presence of NDMA in Zantac. Id. ¶ 74. The FDA separately reached out to GSK in August 2019 to inform GSK about the results of Valisure’s tests and to question the company about the connection between Zantac and NDMA. Id. ¶ 75. In September 2019, the FDA warned the public that there was a risk of developing cancer from Zantac and generic ranitidine due to the presence of NDMA. Id. ¶¶ 82–83. By October 2019, GSK began recalling Zantac from all markets and stopped further distributions of it. Id. ¶¶ 73, 85. In April 2020, the FDA, in addition to other global regulators, ordered a withdrawal of Zantac and all similar drugs that contained ranitidine from the market. Id. ¶¶ 6, 87. Zantac has not returned to the market since. Id. ¶ 88. While the presence of NDMA in Zantac publicly came to light in 2019, Plaintiffs allege that “GSK concealed its knowledge of Zantac’s formation of [NDMA] for decades.” Id. ¶ 6. In 1982, Dr. Richard Tanner, a former GSK scientist, had performed an internal study (the “Tanner Study”) and found that ranitidine can “form[] NDMA in the human stomach” under certain

conditions. Id. ¶¶ 5, 34, 46. In the years that followed the Tanner Study, GSK conducted additional tests and found that ranitidine can degrade and form NDMA in normal storage and transportation conditions. Id. ¶¶ 5, 34. GSK also found that warmer temperatures and moisture can cause discoloration and darkening of Zantac’s otherwise white pills. Id. ¶¶ 49–50. When Valisure’s independent testing revealed the presence of NDMA in Zantac, GSK “confidentially disclosed” certain information to the FDA and EMA in late 2019, including copies of the Tanner Study. Id. ¶¶ 6–7, 81. However, Defendants allegedly continued to mislead investors as to their knowledge of the connection between Zantac and NDMA. Id. ¶ 7. 1. The Products Liability and Personal Injury Litigation Beginning in September 2019, GSK and other manufacturers of ranitidine faced “tens of

thousands of lawsuits by patients who had taken Zantac” and were later diagnosed with cancer. Id. ¶¶ 73, 92. Personal injury plaintiffs filed cases in both state and federal courts across the country. Id. ¶ 93. The cases that proceeded in federal court were ultimately consolidated in a multi-district litigation (“MDL”) proceeding in the Southern District of Florida, In re: Zantac (Ranitidine) Products Liability Litigation, No. 20-MD-02924 (S.D. Fla.). Id. ¶ 94. GSK entered into settlement agreements that resolved certain cases, including a $2.2 billion settlement in October 2024. Id. ¶¶ 154, 157. However, GSK continues to face liability with respect to the suits that are still pending. Id. ¶ 158. 2. The Securities Fraud Class Action On February 4, 2025, Plaintiffs initiated this securities fraud action. See ECF No. 1. Lead Plaintiffs brought suit on behalf of a class, which consists of those who purchased or acquired American Depositary Receipts (“ADRs”) of GSK from February 5, 2020 to August 12, 2022

inclusive (the “Class Period”), and suffered damages as a result of Defendants’ alleged violations of the federal securities laws. ECF No. 25 ¶¶ 25–26, 228. In addition to bringing suit against GSK, Plaintiffs sued two individual Defendants: Emma Walmsley, who has been GSK’s CEO since 2017, and Iain Mackay, GSK’s former CFO from February 2019 through April 2023. Id. ¶¶ 29, 31.1 Plaintiffs asserted three causes of action against Defendants: (1) violations of Section 10(b) of the Exchange Act and Rule 10b-5 (Count I), which Plaintiffs assert against all Defendants; (2) violations of Section 10(b) of the Exchange Act and Rule 10b-5(a), (c) (Count II), which Plaintiffs assert against all Defendants; and (3) violations of Section 20(a) of the Exchange Act (Count III), which Plaintiffs assert only against the individual Defendants. Id. ¶¶ 239–260. Plaintiffs allege that Defendants’ misrepresentations generally fall into four different

buckets: (1) Defendants gave investors the “false impression” that GSK had no knowledge of Zantac’s connection to NDMA until 2019 when the FDA reached out to the company, despite the existence of the 1982 Tanner Study, see id. ¶ 9; (2) Defendants misrepresented the extent of GSK’s liability exposure from pending litigation, see id. ¶ 10; (3) in personal injury litigation, GSK stated that the FDA had previously reviewed the safety of Zantac when approving the medication, yet GSK withheld critical information from the FDA by not disclosing the Tanner Study prior to 2019, see id. ¶ 11; and (4) GSK misrepresented “the need to quantify the range of its liability related to

1 Plaintiffs also initially brought suit against Victoria Whyte, see ECF No. 1, but did not include her as a Defendant in their Amended Complaint, see ECF No. 25. Zantac in its financial statements,” see id. ¶ 12; see also id. ¶¶ 180–217. Defendants’ misrepresentations allegedly caused GSK ADRs to trade at artificially inflated prices.

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Roofers Local No. 149 Pension Fund, on behalf of itself and all others similarly situated v. GSK PLC, et al., Counsel Stack Legal Research, https://law.counselstack.com/opinion/roofers-local-no-149-pension-fund-on-behalf-of-itself-and-all-others-paed-2026.