Clarke v. Yu

CourtCalifornia Court of Appeal
DecidedMarch 16, 2026
DocketD085636
StatusPublished

This text of Clarke v. Yu (Clarke v. Yu) is published on Counsel Stack Legal Research, covering California Court of Appeal primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Clarke v. Yu, (Cal. Ct. App. 2026).

Opinion

Filed 3/16/26

CERTIFIED FOR PUBLICATION

COURT OF APPEAL, FOURTH APPELLATE DISTRICT

DIVISION ONE

STATE OF CALIFORNIA

JOHN CLARKE et al., D085636

Plaintiffs and Appellants,

v. (Super. Ct. No. 37-2023- 00019476-CU-BC-CTL) JIN-QUAN YU et al.,

Defendants and Respondents.

APPEAL from a judgment of the Superior Court of San Diego County, Gregory W. Pollack, Judge. Affirmed. Simpson Thacher & Bartlett, Stephen P. Blake and Jonathan C. Sanders, for Plaintiffs and Appellants. Keker, Van Nest & Peters, R. James Slaughter, Bailey W. Heaps and Niharika Sachdeva, for Defendants and Respondents. The parties, a venture capitalist and two scientists who had worked together on past companies, discussed and took steps toward forming a new company—CHange Pharma, Inc.—to develop and commercialize carbon- hydrogen bond activation, known as C-H activation, technology. When disagreements arose over the amount of initial funding needed, the scientists ultimately obtained funding from other sources. Plaintiffs CHange and John Clarke, the venture capitalist, appeal the summary judgment entered in favor of Defendants Jin-Quan Yu and Benjamin Cravatt, the scientists. We conclude summary judgment was proper on all claims asserted against Defendants. The claims for breach of oral and implied joint venture agreement are barred as a matter of law by the statute of frauds. Plaintiffs contend the statute of frauds does not apply to either oral or implied joint venture agreements. Yet Plaintiffs offer no caselaw, and we are aware of none, that categorically exempts oral or implied joint ventures from the statute of frauds. We publish this opinion to clarify that an oral or implied joint venture agreement is subject to the statute of frauds if the agreement, by its terms, cannot be performed within a year from its making. (Civ. Code, § 1624, subd. (a)(1).) Here, Clarke himself testified “the purpose of the joint venture” was “to develop and ultimately commercialize” Yu’s C-H activation technology. Defendants and a nonparty scientist involved in CHange attested it was not possible to develop this technology in less than one year. Clarke’s uncorroborated and self-serving declaration that CHange “could also have (and did) develop Yu’s technology in . . . less than a year”—unmoored from his proffered experience or any record evidence—does not create a genuine issue of fact sufficient to defeat summary judgment. (King v. United Parcel Service, Inc. (2007) 152 Cal.App.4th 426, 433 (King).) The breach of fiduciary duty claim hinges on a duty arising from an enforceable joint venture agreement, so it falls with the joint venture claims. Summary judgment was also proper on the promissory estoppel claim. The promises Plaintiffs identify are either unenforceable, not grounds for establishing promissory estoppel given the bargain involved, or not clear and unambiguous.

2 Finally, as for the quantum meruit claim, caselaw indicates plaintiffs must perform the at-issue services based on the expectation the defendants would compensate them. (E.g., Miller v. Campbell, Warburton, Fitzsimmons, Smith, Mendel & Pastore (2008) 162 Cal.App.4th 1331, 1344 (Miller).) Because Plaintiffs concede Clarke expected compensation “in the form of his interest in CHange, rather than payment from [Defendants],” summary judgment in Defendants’ favor was appropriate. We thus affirm. I. A. Clarke is a venture capitalist who describes himself as a “sophisticated investor” and an “experienced early stage investor.” Defendants work at The Scripps Research Institute, a nonprofit, publicly funded biomedical research institution. Yu is a chemistry chair and professor at Scripps whose research “focuses on the unexpected discovery of new reactions through . . . C-H activation.” Cravatt is a chemical biology chair at Scripps whose research “focuses on discovering novel therapeutic targets and drugs to treat disease.” In 2011, Cravatt, Clarke, and others worked together on Abide Therapeutics, which was acquired by another company in 2019. In 2014, Defendants, Clarke, and others founded Vividion Therapeutics, Inc., which was acquired by another company in 2021. B. In December 2021, Clarke contacted Yu to arrange a time to meet to “catch up” and “perhaps . . . discuss some new company ideas!” Yu responded that he was looking forward to catching up and was “so excited about my next company focusing more on our C[-]H activation chemistry!”

3 In January 2022, Yu e-mailed Clarke to describe his vision for “this new company.” He explained his desire for it to be “THE company of C-H activation technology, like Apple for [iP]hone, IBM for chips.” Yu expressed his wish to “develop [a] full range of technologies in the long run.” Consequently, the model he wanted to follow was “very different from one biological discovery” or “a one[-]product based chemical company.” Instead, Yu wanted to “get renewable funding to continuously lead the field and develop [a] new generation of technologies.” The next day, in a separate e-mail thread, Clarke told Yu he “couldn’t agree with you more about the potential for your technology and our new company as you said in your email last evening- ‘The Apple’ or ‘IBM’ of the Pharmaceutical industry.” That same month, Clarke contacted an intellectual property attorney about working on “patenting strategy and execution” and mentioned he was “reaching out” to Scripps “to get the licensing/research collaboration agreement in process ASAP.” By February, the company was being referred to as CHange Pharma, Inc. In mid-March, Clarke met separately with Defendants, during which time he claims they orally agreed to a joint venture regarding CHange. In June, Clarke, on CHange’s behalf, entered into a confidential disclosure agreement with Scripps to “contemplate substantive business discussions regarding ‘C[-]H activation tech[nology]’ and a potential business relationship.” Over the ensuing months, Clarke sent Yu and sometimes Cravatt various iterations of capitalization tables outlining different equity distributions in CHange. Yu expressed to someone at Scripps that Clarke’s “[f]irst round of proposal,” which allocated 30% equity in exchange for a

4 $3 million investment, was “far from [Yu’s] expectation,” as he expected a total of $6 million from the first investment round. Soon after, Yu e-mailed Clarke about needing “substantial investment in the first two years.” While Clarke originally offered to invest $3 million in CHange, that number eventually increased to $4 million. In deposition, Cravatt theorized $4 million might have “been enough” had the scope of the company been narrower, but early on he “didn’t understand . . . what type of company [Yu] wanted to build.” By the summer, Clarke understood that Defendants did not consider his proposed financing “sufficient.” For example, in June, Yu messaged Clarke that Cravatt had reservations about the “financing side” of the company, so “we should stick to the early plan between [Defendants] for seed fund of 10 million” because “we will be very tight with 4 [million].” Yu suggested “ask[ing] other investors to co-seed for another 6[ million]” or even having him and Cravatt invest $2 million each.

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Clarke v. Yu, Counsel Stack Legal Research, https://law.counselstack.com/opinion/clarke-v-yu-calctapp-2026.