Yuan v. Johns Hopkins University

157 A.3d 254, 452 Md. 436, 41 I.E.R. Cas. (BNA) 1768, 2017 WL 1161020, 2017 Md. LEXIS 156
CourtCourt of Appeals of Maryland
DecidedMarch 29, 2017
Docket35/16
StatusPublished
Cited by22 cases

This text of 157 A.3d 254 (Yuan v. Johns Hopkins University) is published on Counsel Stack Legal Research, covering Court of Appeals of Maryland primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Yuan v. Johns Hopkins University, 157 A.3d 254, 452 Md. 436, 41 I.E.R. Cas. (BNA) 1768, 2017 WL 1161020, 2017 Md. LEXIS 156 (Md. 2017).

Opinion

Greene, J.

In this case, Petitioner, Daniel S. Yuan, M.D. (“Dr. Yuan”), challenges the Court of Special Appeals’ conclusion that there was no clear public policy mandate to support a claim for wrongful termination for reporting research misconduct in a federally funded project at Respondent institution Johns Hopkins University School of Medicine (“JHU”), a scientific research institution. Dr. Yuan was a researcher employed by JHU. The suit arises from Dr. Yuan’s allegation that he was wrongfully terminated in retaliation for his repeated protests *440 of research misconduct in violation of 42 U.S.C. § 289b and 42 C.F.R. Part 93. 1

We hold that these provisions regarding research misconduct do not provide a clear public policy to support a tort claim for wrongful termination of employment. The self-regulating provisions direct the federally funded scientific institutions to provide procedures to investigate allegations of research misconduct, take appropriate action, and address retaliation. See 42 C.F.R. §§ 93.300-93.304. The scientific institution, not this Court, is in the best position and has the expertise to determine whether the research results of its employees amounted to impermissible research misconduct or permissible error or differences of opinion. Dr. Yuan did not follow the protocol outlined in JHU’s policies for research misconduct claims. Further, Dr. Yuan acknowledged in his brief filed in this case that the regulations do not provide him with legal redress in the form of damages and he therefore seeks tort damages based on a theory of wrongful termination. However, there was no clear violation of the research misconduct regulations to warrant a cause of action for wrongful termination.

*441 Dr. Yuan also alleged conversion because after the termination of his employment, he was denied access to stored research materials he had collected. However, JHU owned the research materials pursuant to its policy, and it is well settled that a party may not convert that which it owns. Therefore, we affirm the judgment of the Court of Special Appeals.

FACTUAL AND PROCEDURAL BACKGROUND

Dr. Yuan alleged in a lengthy amended complaint the following facts:

Dr. Yuan was Board-certified in General Pediatrics and Pediatric Gastroenterology. He was employed by JHU as a researcher with the Pediatrics Faculty. In July 2001, he joined the lab of Dr. Jef Boeke (“Dr. Boeke”), a Professor in the Department of Molecular Biology and Genetics and the head of a yeast genetics lab. The lab was largely funded through the National Institute of Health (“NIH”), an agency of the United States Department of Health and Human Services (“DHHS”). Between February 2002 and June 2011, the NIH provided over $11.8 million to the lab for research on the Synthetic Lethality Analyzed by Microarray (“SLAM”) project, which was an ambitious yeast genetics research project using a novel methodology, as well as a $34 million grant for a project related to the SLAM research. In Dr. Boeke’s lab, Dr. Yuan was initially responsible for developing the computational infrastructure to manage the SLAM project’s massive data-sets.

When SLAM entered its Production phase, in 2004, Dr. Yuan discovered and reported to the Production team a concern that contaminating traces of DNA from preceding SLAM experiments had led to false positive results. However, the team resisted his concerns and suggestions for addressing the issue and instead began withholding data files from him.

Dr. Yuan stated that from 2005 through 2011, he repeatedly reported research misconduct concerning the yeast genetics research claiming that the SLAM researchers were falsifying the results. In particular, on November 28, 2005, Dr. Yuan *442 emailed Dr. Boeke about issues he identified in research completed by Xuewen Pan (“Dr. Pan”), a postdoctoral fellow in Dr. Boeke’s lab. Dr. Yuan stated that Dr. Pan’s “genes are preselected,” and that continuing with those research projects “will only generate more useless data.” He also stated that the SLAM team had already established that “most of the [SLAM Project] hits being identified are bogus.”

Dr. Pan’s research was published in a biomedical journal, Cell, with Dr. Boeke as the senior author in early 2006. Moreover, Dr. Boeke cited Dr. Pan’s research when he applied for grant renewals through the NIH. After the NIH renewed the SLAM project funding in late 2006, Dr. Boeke issued a new organizational chart which had the effect of excluding Dr. Yuan from extensive involvement with the SLAM research. Dr. Yuan maintained that he protested his lack of a definite professional role in the SLAM Project and found himself increasingly marginalized and excluded from the data management.

Between 2006 and 2008, the SLAM research was unsuccessful; the lab did not have significant results to report to NIH. Dr. Boeke asked other researchers to review the SLAM project data, excluding Dr. Yuan. The researchers corroborated Dr. Yuan’s findings and found that the data had an extraordinarily high “False Discovery Rate.” In the summer of 2008, Dr. Boeke decided not to renew the NIH grant for SLAM, although, some funding remained available to operate SLAM.

In January 2009, after analyzing Dr. Pan’s microarray data from his Cell publication, Dr. Yuan determined that Dr. Pan could not have obtained the results he claimed. His conclusion was not that Dr. Pan fabricated the results; instead, Dr. Yuan asserted that Dr. Pan likely conducted the experiment with preconceptions of the results he wanted to find—and then managed to find those results. Dr. Yuan also concluded similarly with respect to a paper published in 2008 by Dr. Yu-yi Lin (“Dr. Lin”) in Genes & Development In January of 2009, Dr. Yuan also notified both Dr. Boeke and SLAM’s project *443 manager, Dr. Meluh, of the problems with Dr. Pan’s 2006 and Dr. Lin’s 2008 papers.

Dr. Yuan was informed by Dr. Boeke in December 2009 that Dr. Boeke would not be renewing his faculty contract for 2011, unless he was able to secure self-sustaining funding within the next year. Dr, Boeke explained this was due to limited funding; however, at that time, Dr. Boeke established three new full-time positions with the SLAM Project for three other individuals.

Dr. Yuan again reported problems with SLAM research, in January 2010, at a lab seminar where he identified bizarre zigzag patterns after plotting data for individual genes in SLAM’s Production data in chronological order. Dr. Yuan concluded that these zigzags were both non-random and unpredictable and were also large enough to masquerade as the genetic interactions that SLAM was looking for; thus, according to Dr. Yuan, attempts to interpret SLAM’s data were doomed to fail. Further, during the last week of the NIH funding of SLAM, on June 29, 2010, Dr. Yuan wrote to Dr.

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157 A.3d 254, 452 Md. 436, 41 I.E.R. Cas. (BNA) 1768, 2017 WL 1161020, 2017 Md. LEXIS 156, Counsel Stack Legal Research, https://law.counselstack.com/opinion/yuan-v-johns-hopkins-university-md-2017.