Warren v. The Children's Hospital Corporation

Court of Appeals for the First Circuit·Decided September 8, 2026·No. 23-1158·Unpublished

Opinion

Not for Publication in West's Federal Reporter

United States Court of Appeals For the First Circuit

No. 23-1158 LUIGI WARREN,

Plaintiff, Appellant,

v.

THE CHILDREN'S HOSPITAL CORPORATION, Defendant, Appellee.

APPEAL FROM THE UNITED STATES DISTRICT COURT FOR THE DISTRICT OF MASSACHUSETTS

[Hon. Donald L. Cabell, U.S. Magistrate Judge]

Before

Gelpí, Kayatta, and Montecalvo, Circuit Judges.

Luigi Warren, pro se.

Theodore J. Folkman and Rubin and Rudman, LLP on brief for appellee.

September 8, 2026

PER CURIAM. This appeal concerns the royalties owed to Dr. Luigi Warren, the co-inventor of a significant advance in the field of mRNA reprogramming that was subsequently licensed to biotechnology company Moderna. The district court granted summary judgment to defendant The Children's Hospital Corporation ("Children's Hospital") and denied as futile Dr. Warren's motion to amend his complaint. For the reasons that follow, we vacate the award of summary judgment as to Dr. Warren's breach of contract claim and remand to the district court.

I.

From 2008 to 2010, while employed by the Immune Disease Institute (IDI),1 Dr. Warren invented a method for safely reprogramming skin cells into stem cells using synthetic mRNA. At the time, IDI had a royalty-sharing policy that granted one-third of licensing revenue to the inventors of licensed technology and called for the inventor's share of any equity received in exchange for licensing rights to be promptly distributed to the inventor (the "IDI policy"). The IDI policy also provided that IDI's trustees "retain the discretion to amend this Policy from time to time to fulfill [its] purposes."2

1 At the time of Dr. Warren's employment, "IDI was an independent, Harvard-affiliated research institution" on the Harvard Medical School campus.

2 The stated purposes of the IDI policy are to: (1) "benefit the public by facilitating commercial development and utilization of inventions, discoveries and other [t]echnology," (2) "encourage

After Dr. Warren's invention, but before that invention was licensed to Moderna in late 2010, IDI and Children's Hospital executed an Affiliation Agreement in anticipation of an eventual merger. In that Agreement, the parties agreed to apply Children's Hospital's royalty-sharing policy (the "Children's Hospital policy") rather than IDI's to any intellectual property that had not yet been licensed as of the Agreement's effective date of February 20, 2009 -- even if that intellectual property had already been invented. The Children's Hospital policy allocated a different percentage of royalties to inventors and dictated a different treatment of equity than the IDI policy. For example, under the Children's Hospital policy, Children's Hospital would pay an inventor who is no longer employed by Children's Hospital 35% of licensing proceeds "up to" $500,000, then 25% of proceeds "above" $500,000.

the creativity and innovation of current staff, and encourage the recruitment and retention of talented and innovative staff," (3) "provide incentive to researchers to be productive and recognize individual accomplishment," (4) "foster scholarly pursuits and principles of academic freedom," (5) "encourage researchers to disclose discoveries in a timely manner in order to protect the intellectual property interests of IDI," (6) "provide guidelines for negotiating, preparing and implementing contracts with outside sponsors, collaborators and licensees," (7) "provide for equitable allocation of responsibilities and financial rewards among inventors, researchers, IDI and any other entity" involved in inventions, discoveries, or technology, and (8) "provide support for IDI's mission of excellence in clinical care, teaching and research."

In 2011, after Dr. Warren had left IDI's employ and assigned his "entire right, title, and interest" in his invention to the company in 2010, IDI employee Ryan Dietz contacted him seeking a second assignment of the same invention. When Dr. Warren asked for the document that required him to make such an assignment, Dietz sent him an excerpt from the IDI policy. When Dr. Warren asked for the relevant policy governing royalties, Dietz again responded with an excerpt from the IDI policy. And when Dr. Warren refused to complete the second assignment, General Counsel for Children's Hospital sent him the full IDI policy and told him he was obligated to execute the assignment. Simultaneously, Children's Hospital's outside counsel threatened to sue Dr. Warren, alleging he had violated his obligations under the IDI policy and attaching a draft complaint asserting a claim for breach of contract, namely, breach of the IDI policy. Shortly thereafter, Dr. Warren executed the second assignment.3 Fast forward six years to 2017: With rumors of an initial public offering from Moderna swirling, Dr. Warren -- wondering whether the Moderna licensing agreement for his invention had included equity -- called Dietz, now a Children's Hospital employee, to ask about that licensing agreement. At that point, Dietz informed Dr. Warren, seemingly

The record reflects that Dr. Warren actually executed two 3

assignments in 2011 but is not clear as to why.

for the first time, that the repeated references to the IDI policy in 2011 were in error, and that the Children's Hospital policy -- not IDI's -- governed his royalties and equity in the licensing deal to Moderna. The Children's Hospital policy entitled Dr. Warren to a lesser share of royalties and directed a different, and in Dr. Warren's view, less favorable, treatment of equity than the IDI policy. Displeased, Dr. Warren sued Children's Hospital as IDI's successor in interest.4 Proceeding pro se, he asserted claims of breach of contract and promissory estoppel, arguing that the IDI policy applies to his invention.

In due course, Children's Hospital moved for summary judgment. The court initially denied that motion without a written order in 2019. When Dr. Warren later learned that Children's Hospital had sold equity in Moderna it had received as part of the licensing agreement and distributed the proceeds to Dr. Warren rather than distributing the equity itself, he moved to amend his complaint to add a cause of action for conversion. But then the court issued a written memorandum and order vacating its prior order, granting Children's Hospital's motion for summary judgment on all claims, and denying as futile Dr. Warren's motion to amend.5

4 IDI dissolved in 2012 and merged into Children's Hospital.

5 In addition to Dr. Warren's claims of breach of contract and promissory estoppel, the court also granted summary judgment to Children's Hospital on a "possible negligent misrepresentation claim."

In so doing, the court held that, even assuming the IDI policy was a binding contract, IDI had exercised its right under that contract to unilaterally amend the policy when it executed the Affiliation Agreement with Children's Hospital; accordingly, the Children's Hospital policy governed the royalties and equity to which Dr. Warren was entitled.6 The court characterized Dietz's misrepresentations in 2011 as "regrettable" but ultimately legally immaterial. Dr. Warren timely appealed, again proceeding pro se.

II.

We review a grant of summary judgment de novo. Salmon v. Lang, 57 F.4th 296, 308 (1st Cir. 2022). Summary judgment is only warranted if "the record shows 'there is no genuine dispute as to any material fact and the movant is entitled to judgment as a matter of law.'" Id. (quoting Fed. R. Civ. P. 56(a)). "A dispute is 'genuine' if 'a jury can reasonably interpret the evidence in the non-movant's favor,' and a fact is 'material' if it is 'one that might affect the outcome of the suit under governing law.'" Id. at 308 n.6 (quoting Reyes-Orta v. P.R. Highway & Transp. Auth., 811 F.3d 67, 73 (1st Cir. 2016)). In assessing a summary judgment motion, we "evaluate the facts and draw all reasonable inferences from the record in the light most

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