Teva Pharmaceuticals, Industries, Ltd. v. Food & Drug Administration

355 F. Supp. 2d 111, 2004 U.S. Dist. LEXIS 26233, 2004 WL 3037715
CourtDistrict Court, District of Columbia
DecidedDecember 23, 2004
DocketCIV.A.04-1416(RBW)
StatusPublished
Cited by12 cases

This text of 355 F. Supp. 2d 111 (Teva Pharmaceuticals, Industries, Ltd. v. Food & Drug Administration) is published on Counsel Stack Legal Research, covering District Court, District of Columbia primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Teva Pharmaceuticals, Industries, Ltd. v. Food & Drug Administration, 355 F. Supp. 2d 111, 2004 U.S. Dist. LEXIS 26233, 2004 WL 3037715 (D.D.C. 2004).

Opinion

MEMORANDUM OPINION

WALTON, District Judge.

The plaintiffs filed this action to challenge a decision by the Food and Drug Administration (“FDA”), which permits the sale of brand generic drugs 1 during the generic exclusivity period provided for in 21 U.S.C. § 355(j)(5)(B)(iv)(I). Verified Amended Complaint (“Compl.”) ¶¶ 119-24. 2 The parties have filed cross-motions for summary judgment. Currently before the Court are (1) the Plaintiffs’ Memorandum of Law in Support of Their Motion for Partial Summary Judgment (“Pis.’ Mem.”); (2) the Federal Defendants’ Memorandum in Support of Motion to Dismiss Amended Complaint or, in the Alternative, for Summary Judgment; and in Opposition to Plaintiffs’ Motion for Partial Summary Judgment (Defs.’ Mem.); and (3) the Memorandum of Law in Opposition to Defendants’ Motion to Dismiss and in Further Support of Plaintiffs’ Motion for Summary Judgment (“Pis.’ Reply”). 3 For the following reasons, this Court will grant the *113 federal defendants’ and the intervenor defendants’ motions for summary judgment and deny the plaintiffs’ motion.

I. Statutory Scheme

Prior to the passage of the Federal Food, Drug and Cosmetic Act (“FDCA”), 21 U.S.C. § 301 et. seq., commonly referred to as the Hatch-Waxman Amendments, all drug manufacturers — brand-name and generic — were required to conduct controlled human clinical studies to demonstrate that the drug that they wanted to introduce into the market was safe and effective. Allergan, Inc. v. Alcon Lab., Inc., 324 F.3d 1322, 1325 (Fed.Cir.2003). This requirement delayed the entry into the market of both new drugs and generic versions of such drugs. Id. The Hatch-Waxman Amendments sought to address this situation by striking “a balance between two competing policy interests: (1) inducing pioneering research and development of new drugs and (2) enabling competitors to bring low-cost, generic copies of those drugs to the market.’ ” Allergan, 324 F.3d at 1325 (citing Andrx Pharms., Inc. v. Biovail Corp., 276 F.3d 1368, 1371 (Fed.Cir.2002)). Under the Hatch-Waxman Amendments, only companies seeking to market a drug that has never been approved for use in the United States are required to submit a New Drug Application (“NDA”). A NDA is required to contain scientific data demonstrating the safety and effectiveness of the new drug. 21 U.S.C. § 355(a), (b), (c). However, companies seeking td market a generic drug of a previously approved drug no longer need to conduct human clinical tests. Instead, the generic drug manufacturer can submit an Abbreviated New Drug Application (“ANDA”) demonstrating, among other requirements, that the generic version of the drug is the bioequi-valent to the NDA approved version of the drug. 21 U.S.C. §§ 355, 360cc; 35 U.S.C. §§ 156, 271, 282.

The approval of an ANDA depends, in part, upon the applicant submitting “a certification ... with- respect to each patent which claims [a] listed drug [previously approved by the Secretary of Health and Human Services (‘HHS’) for safety and effectiveness or whose approval has been withdrawn or suspended] or which claims a use for such a listed drug for which the applicant is seeking approval 21 U.S.C. §§ 355(j)(2)(A)(vii), 355(7). In, addition, the certification must state one of the following:

(I) that the required patent information relating to such patent has not been filed;
(II) that such patent has expired;
(III) that the patent will expire on a particular date;
(IV) that such patent is invalid or will not be infringed upon by the drug for which approval'is sought.

35 U.S.C. § 355(j)(2)(A)(vii). “If [a] certification is made under paragraph I or II indicating that patent information pertaining to the drug or its use has not been filed with the FDA or that the patent has expired, approval of the ANDA may be made effective immediately.” Barr Labs. Inc. v. Thompson, 238 F.Supp.2d 236, 240 (D.D.C.2002) (citing 21 U.S.C. § 355(j)(5)(B)(i)). A paragraph III certification indicates that the applicant seeks approval to market the drug only after the applicable patent has expired. 21 U.S.C. § 355(j)(5)(B)(ii). When the ANDA contains a paragraph IV certification, the applicant must also provide notice of the paragraph IV certification to the NDA holder and the patent owner, and describe the, factual and legal basis for the applicant’s opinion that an active patent is invalid or not infringed.- 21 U.S.C. § 355(j)(2)(B); 21 C.F.R. § 314.95. Under the Hatch-Waxman amendments, filing an ANDA with a paragraph IV certification is *114 deemed to be a “highly artificial” act of infringement. 35 U.S.C. § 271(e)(2)(A); Eli Lilly & Co. v. Medtronic Inc., 496 U.S. 661, 678, 110 S.Ct. 2683, 110 L.Ed.2d 605 (1990). This act of infringement permits the NDA holder and the patent owner to sue the ANDA applicant before the drug is placed on the market, which helps expedite the generic drug reaching the marketplace. Allergan, 324 F.3d at 1326-27. 4

Because of the likelihood of litigation, the filing of a paragraph IV certification can be costly. Thus, to encourage the investment in ANDA generic drugs, Congress granted an economic incentive to the first generic company to file a paragraph IV certification. Pharmachemie B.V. v. Barr Labs., Inc., 276 F.3d 627, 629 (D.C.Cir.2002). Under the Hatch-Wax-man Amendments, the first drug manufacturing company to file a paragraph IV certification receives a 180-day period in which the first filer is entitled to be the only provider of generic versions of the drug in the market place (“generic exclusivity period”). 21 U.S.C.

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Bluebook (online)
355 F. Supp. 2d 111, 2004 U.S. Dist. LEXIS 26233, 2004 WL 3037715, Counsel Stack Legal Research, https://law.counselstack.com/opinion/teva-pharmaceuticals-industries-ltd-v-food-drug-administration-dcd-2004.