Siegler v. Sorrento Therapeutics, Inc.

CourtCourt of Appeals for the Federal Circuit
DecidedJuly 20, 2021
Docket20-1435
StatusUnpublished

This text of Siegler v. Sorrento Therapeutics, Inc. (Siegler v. Sorrento Therapeutics, Inc.) is published on Counsel Stack Legal Research, covering Court of Appeals for the Federal Circuit primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Siegler v. Sorrento Therapeutics, Inc., (Fed. Cir. 2021).

Opinion

Case: 20-1435 Document: 62 Page: 1 Filed: 07/20/2021

NOTE: This disposition is nonprecedential.

United States Court of Appeals for the Federal Circuit ______________________

SARA ELIZABETH SIEGLER, SARA ELIZABETH SIEGLER, Plaintiffs-Appellants

v.

SORRENTO THERAPEUTICS, INC., TNK THERAPEUTICS, INC., BDL PRODUCTS, INC., CARGENIX HOLDINGS LLC, PROSPECT CHARTERCARE ROGER WILLIAMS MEDICAL CENTER LLC, HENRY JI, STEVEN C. KATZ, TUFTS MEDICAL CENTER, Defendants-Appellees

RICHARD PAUL JUNGHANS, Defendant ______________________

2020-1435 ______________________

Appeal from the United States District Court for the Southern District of California in No. 3:18-cv-01681-GPC- MSB, Judge Gonzalo P. Curiel. ______________________

Decided: July 20, 2021 ______________________ Case: 20-1435 Document: 62 Page: 2 Filed: 07/20/2021

SARA ELIZABETH SIEGLER, Bedford, OH, pro se.

PETER STONE, Paul Hastings LLP, Palo Alto, CA, for defendants-appellees Sorrento Therapeutics, Inc., TNK Therapeutics, Inc., BDL Products, Inc., Cargenix Holdings LLC, Henry Ji. Also represented by KEVIN JAMES WHITE.

CHARLES M. MCMAHON, McDermott Will & Emery LLP, Chicago, IL, for defendants-appellees Prospect Char- tercare Roger Williams Medical Center LLC, Steven C. Katz. Also represented by MICHAEL P. CHU; JIAXIAO ZHANG, Irvine, CA.

DAVID ALAN WOLLIN, Hinckley, Allen & Snyder LLP, Providence, RI, for defendant-appellee Tufts Medical Cen- ter. ______________________

Before PROST, SCHALL, and O’MALLEY, Circuit Judges. O’MALLEY, Circuit Judge. Sara Elizabeth Siegler—and, purportedly, Sara Eliza- beth Siegler (“SES”), a sole proprietorship that she owns and operates—appeals several decisions of the United States District Court for the Southern District of Califor- nia. These include the denial of her motion for default judgment, the dismissals of her First and Second Amended Complaints, and the denials of her motions for reconsider- ation and motion for leave to amend. See Siegler v. Sor- rento Therapeutics, Inc. (Siegler I), No. 3:18-cv-01681-GPC- NLS, 2018 WL 9516052 (S.D. Cal. Oct. 31, 2018); Siegler v. Sorrento Therapeutics, Inc. (Siegler II), No. 3:18-cv-01681- GPC-NLS, 2019 WL 581719 (S.D. Cal. Feb. 13, 2019); Sieg- ler v. Sorrento Therapeutics, Inc. (Siegler III), No. 3:18-cv- 01681-GPC-MSB, 2019 WL 1574321 (S.D. Cal. Apr. 11, 2019); Siegler v. Sorrento Therapeutics, Inc. (Siegler IV), No. 3:18-cv-01681-GPC-NLS, 2019 WL 2549248 (S.D. Cal. June 20, 2019); Siegler v. Sorrento Therapeutics, Inc. Case: 20-1435 Document: 62 Page: 3 Filed: 07/20/2021

SIEGLER v. SORRENTO THERAPEUTICS, INC. 3

(Siegler V), No. 3:18-cv-01681-GPC-NLS, 2019 WL 3532294 (S.D. Cal. Aug. 2, 2019); Siegler v. Sorrento Ther- apeutics, Inc. (Siegler VI), No. 3:18-cv-01681-GPC-MSB, 2019 WL 6877594 (S.D. Cal. Dec. 17, 2019). Because we are unpersuaded by Siegler’s arguments, we affirm. I. BACKGROUND A. Factual Background Given the procedural posture of this matter, we assume the facts Siegler alleges are true. Siegler, a resident of Ohio, owns and operates an Ohio-based sole proprietorship in her own name, SES. According to Siegler, SES is “an early stage micro-entity without any marketed pharmaceu- tical products to date” and a “potential participant in the CAR T cell pharmaceutical market both domestically and abroad.” 1 Siegler II, 2019 WL 581719, at *2. In 2013, Sieg- ler began collaborating with Dr. Richard Paul Junghans on developing new CAR T cell-based therapeutics for virology and oncology indications. See id. As part of the collabora- tion, Siegler authored two scientific articles, “In Vivo Test- ing of 3rd Generation Anti-CEA Designer CAR T Cells with Bcl-XL in Pancreatic Cancer” and “Phase 1b/2 Study of [2nd Generation] Anti-CEA Designer CAR T Cells in Breast Cancer.” 2 Id. In 2015, Siegler registered these ar- ticles with the United States Copyright Office. Id. Around this time, Siegler made plans to use a facility at Prospect CharterCARE Roger Williams Medical Center LLC (“RWMC”) to develop her research. Id. Meanwhile, Dr. Junghans became employed on a part- time basis at Tufts Medical Center, a non-profit medical institution that is incorporated and has its principal place

1 CAR T cells, or CARs, are chimeric antigen recep- tor T cells. CAR T cells are a potential cancer treatment. 2 Anti-CEA CAR T cells target the carcinoembryonic antigen (“CEA”) on tumor cells. Case: 20-1435 Document: 62 Page: 4 Filed: 07/20/2021

of business in Massachusetts. See id. at *2, *17. Dr. Junghans also founded a company, BDL Products, Inc. Id. at *2. TNK Therapeutics, Inc., a wholly owned subsidiary of Sorrento Therapeutics, Inc., later acquired BDL Prod- ucts. See id. at *3. They executed a Stock Purchase Agree- ment that was allegedly contingent on an exclusive license to several CARs between TNK Therapeutics and CARgenix Holdings LLC. Id. According to Siegler, these agreements contained a restrictive covenant that prohibited Dr. Junghans and Tufts Medical Center from working with her on their original collaboration. Id. Siegler ultimately ter- minated her relationship with Dr. Junghans. Id. In 2016, Sorrento Therapeutics and TNK Therapeutics entered into an Immunotherapy Research Collaboration Agreement with RWMC. Id. According to Siegler, the agreement effectively precluded her from using the RWMC facility at which she planned to develop her research. Id. A 2018 extension of the agreement expressly placed the op- eration of the RWMC facility under Sorrento Therapeu- tics’s management. See id. Sorrento Therapeutics also executed a Sponsored Re- search Agreement with Tufts Medical Center. Id. at *4. Under that contract, Sorrento Therapeutics awarded Tufts Medical Center funding for “discrete research to be con- ducted by Dr. Junghans at Tufts Medical Center in Boston, Massachusetts.” Id. The two entities executed a second Sponsored Research Agreement the next year. See id. Around this time in 2016, Sorrento Therapeutics and TNK Therapeutics entered into several more contracts with other companies. These included joint-venture agree- ments to commercialize anti-CEA CAR T constructs abroad and licenses to CAR T constructs. See id. Additionally, in 2016, RWMC initiated a clinical trial to study the use of anti-CEA CAR T cells as a potential treatment for liver and pancreatic cancers. Id. at *3. Case: 20-1435 Document: 62 Page: 5 Filed: 07/20/2021

SIEGLER v. SORRENTO THERAPEUTICS, INC. 5

Finally, RWMC filed two U.S. patent applications, No. 15/210,818 (“the ’818 application”) and No. 15/099,370 (“the ’370 application”). Id. at *4. Tufts Medical Center also filed a provisional application, Application No. 62/362,825 (“the ’825 application”). See id. These applications related to anti-CEA CAR T cell constructs. The U.S. Patent and Trademark Office has only granted the ’818 application, which issued on September 11, 2018, as U.S. Patent No. 10,071,118 (“the ’118 patent”). See id. B. Procedural History 1. Dismissal of the First Amended Complaint On July 24, 2018, Siegler and SES sued Sorrento Ther- apeutics, TNK Therapeutics, CARgenix Holdings, BDL Products, and Sorrento Therapeutics’s CEO Dr. Henry Ji (collectively, the “Sorrento Defendants”), as well as the Board of Directors of Sorrento Therapeutics, RWMC, an eq- uity owner of CARgenix Holdings named Dr. Steven C. Katz, and Dr. Junghans. On August 20, 2018, Siegler and SES filed a First Amended Complaint as a matter of right, naming Tufts Medical Center as an additional defendant. According to the First Amended Complaint, the defend- ants unlawfully researched anti-CEA CAR T cell con- structs, mentioned them in corporate presentations, and filed related patent applications. Based on these allega- tions, Siegler asserted claims of copyright infringement and trade secret misappropriation, as well as a Fifth Amendment takings claim.

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