Phillip W. Berman, Timothy J. Gregory, Laurence A. Lasky, Gerald R. Nakamura, Eric J. Patzer, John S. Patton, and Ellen S. Vitetta v. Gerard M. Housey

291 F.3d 1345, 63 U.S.P.Q. 2d (BNA) 1023, 2002 U.S. App. LEXIS 10256, 2002 WL 1068293
CourtCourt of Appeals for the Federal Circuit
DecidedMay 29, 2002
Docket01-1311
StatusPublished
Cited by16 cases

This text of 291 F.3d 1345 (Phillip W. Berman, Timothy J. Gregory, Laurence A. Lasky, Gerald R. Nakamura, Eric J. Patzer, John S. Patton, and Ellen S. Vitetta v. Gerard M. Housey) is published on Counsel Stack Legal Research, covering Court of Appeals for the Federal Circuit primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Phillip W. Berman, Timothy J. Gregory, Laurence A. Lasky, Gerald R. Nakamura, Eric J. Patzer, John S. Patton, and Ellen S. Vitetta v. Gerard M. Housey, 291 F.3d 1345, 63 U.S.P.Q. 2d (BNA) 1023, 2002 U.S. App. LEXIS 10256, 2002 WL 1068293 (Fed. Cir. 2002).

Opinion

LOURIE, Circuit Judge.

Phillip W. Berman, Timothy J. Gregory, Laurence A. Lasky, Gerald R. Nakamura, Eric J. Patzer, John S. Patton, and Ellen S. Vitetta (collectively, “Berman”) appeal from the decision of the United States Patent and Trademark Office Board of Patent Appeals and Interferences entering judgment in favor of Gerard M. Housey and dismissing Berman’s unpatentability motion as moot. Berman v. Housey, Inter. No. 104,347, slip op. at 17 (Bd. Pat. App. & Inter. Dec. 21, 2000) (“Berman II”). Because the Board did not err in refusing to consider Berman’s unpatenta-bility motion and in entering judgment in favor of Housey, we affirm.

BACKGROUND

Berman’s U.S. Patent Application 08/953,550 is directed to, inter alia, a method of determining whether a substance inhibits the binding of T4 receptors to the T cell binding domain of gpl20. Id. at 2. That application was accorded the benefit of the February 20, 1987, filing date of one of Berman’s earlier copending applications. On October 17, 1997, Ber-man filed a preliminary amendment canceling all the claims in the '550 application and introducing new independent claim 64 and dependent claims 65 and 66. Id. Ber-man also requested that an interference be declared with one of Housey’s pending applications, which later issued on November 18, 1997, as U.S. Patent 5,688,655 (“Hous-ey III”). Id.

The examiner rejected claims 64-66 on various grounds, and Berman responded by canceling claims 65 and 66 and amending claim 64. Id. Amended claim 64, presently the sole remaining claim in the '550 application, reads as follows:

64. A method of identifying an anti-gpl20 monoclonal antibody that is an inhibitor of the binding of T4 receptor to the T cell binding (TCB) domain of gpl20 by blocking or binding said TCB domain, which method comprises:
(a) providing a CHO cell which has been transformed to produce T4 receptor relative to a control CHO cell which does not produce T4 receptor, and wherein production of T4 receptor enhances the ability to bind to the TCB domain of gpl20 in the transformed cell, which ability is greater in said transformed cell than in said control cell,
(b) treating said transformed cell with an anti-gpl20 monoclonal antibody and gpl20, and
(c) examining the treated transformed cell to determine whether inhibition of the binding of T4 receptor to the TCB domain of gpl20 has occurred in response to said anti-gpl20 monoclonal antibody of (b).

The examiner found claim 64, as amended, to be patentable, and was of the opinion that it interfered with the claims of Hous-ey III as well as the claims of two other Housey patents: U.S Patent 4,980,281 (“Housey I”), issued on December 25, 1990, and U.S. Patent 5,266,464 (“Housey II”), issued on November 30, 1993. Id. at *1348 3. After the examiner forwarded Berman’s application to the Board, the present interference was declared between claim 64 of the '550 application and claims 1 and 22 of Housey I, claims 1 and 5 of Housey II, and claim 1 of Housey III. Id. Claim 1 of Housey I is representative of the claims in Housey I involved in this appeal, and it reads as follows:

1. A method of determining whether a substance is an inhibitor or activator of a protein whose production by a cell evokes a responsive change in a pheno-typic characteristic other than the level of said protein in said cell per se, which comprises:
(a) providing a first cell line which produces said protein and exhibits said phenotypic response to the protein;
(b) providing a second cell line which produces the protein at a lower level than the first cell line, or does not produce the protein at all, and which exhibits said phenotypic response to the protein to a lesser degree or not at all;
(c) incubating the substance with the first and second cell lines; and
(d) comparing the phenotypic response of the first cell line to the substance with the phenotypic response of the second cell line to the substance.

Housey I, col. 24, 11. 46-63. The claims of Housey II involved here are identical to those in Housey I, except that they require the use of CHO cell lines. Housey II, col. 31, 1. 32 to col. 32, 1. 6. Claim 1 of Housey III is also similar to the claims in Housey I, except that the screening method claimed therein utilizes a control cell, which obviates the need to use two separate cell lines to determine whether a particular substance acts to inhibit or activate cell proteins that cause a phenotypic change in the cell being analyzed. That claim reads as follows:

1. A method of determining whether a substance is an inhibitor or an activator of a protein, which comprises:
(a) providing a test cell which overproduces a selected protein relative to a control cell which produces said protein at a lower level or essentially does not produce the protein, and wherein production of said protein in said test cell evokes a responsive change in a pheno-typic characteristic, other than the level of said protein in said cell, per se, which is comparatively greater than in said control cell,
(b) treating said test cell containing the overproduced selected protein with said substance, and
(c) examining the treated test cell to determine whether it exhibits a change in said phenotypic characteristic in response to said substance.

Housey III, col. 29,11. 27-41.

The Board set July 23, 1999, as the expiration date for the filing of any preliminary motions. Berman v. Housey, Inter. No. 104,347, slip op. at 2 (Bd. Pat.App. & Inter. Apr. 7, 1999). On April 19, 1999, Housey filed a preliminary motion under 37 C.F.R. § 1.633(a), which the Board agreed to hear on an expedited basis, asserting that claim 64 of the '550 application was barred under 35 U.S.C. § 135(b) because that claim was not made within one year of the issuance of Housey I and Housey II. Berman II at 3. Berman filed an opposition to that motion, arguing that original claim 27, filed on February 20, 1987, was directed to substantially the same subject matter as Housey’s involved claims, and thus that the bar of § 135(b) was inapplicable. Id. at 3^4. Claim 27, which is directed to a particular type of antibody rather than a screening method as in the claims set forth above, reads as follows:

*1349 27. An antibody which has the TCB domain binding characteristics of monoclonal antibody 5C2E5 (ATCC-).

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291 F.3d 1345, 63 U.S.P.Q. 2d (BNA) 1023, 2002 U.S. App. LEXIS 10256, 2002 WL 1068293, Counsel Stack Legal Research, https://law.counselstack.com/opinion/phillip-w-berman-timothy-j-gregory-laurence-a-lasky-gerald-r-cafc-2002.