Flavia Pichiorri v. Arthur Burghes

CourtCourt of Appeals for the Sixth Circuit
DecidedDecember 19, 2025
Docket24-3918
StatusPublished

This text of Flavia Pichiorri v. Arthur Burghes (Flavia Pichiorri v. Arthur Burghes) is published on Counsel Stack Legal Research, covering Court of Appeals for the Sixth Circuit primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Flavia Pichiorri v. Arthur Burghes, (6th Cir. 2025).

Opinion

RECOMMENDED FOR PUBLICATION Pursuant to Sixth Circuit I.O.P. 32.1(b) File Name: 25a0352p.06

UNITED STATES COURT OF APPEALS FOR THE SIXTH CIRCUIT

┐ FLAVIA PICHIORRI, PH.D., │ Plaintiff-Appellant, │ │ v. │ > No. 24-3918 │ ARTHUR BURGHES; BRANDON BIESIDADECKI; │ JONATHAN DAVIS; JILL A. RAFAEL-FORTNEY; YUTONG │ ZHAO; THOMAS HUND; LOREN WOLD; COLLEEN RUPP; │ PETER MOHLER; OHIO STATE UNIVERSITY BOARD OF │ TRUSTEES, │ Defendants-Appellees. │ ┘

Appeal from the United States District Court for the Southern District of Ohio at Columbus. No. 2:23-cv-01442—Edmund A. Sargus, Jr., District Judge.

Decided and Filed: December 19, 2025

Before: WHITE, STRANCH, and MURPHY, Circuit Judges. _________________

COUNSEL

ON BRIEF: Renny J. Tyson, RENNY J. TYSON CO., LPA, Columbus, Ohio, William W. Patmon, III, THE PATMON LAW FIRM, LLC, Columbus, Ohio, for Appellant. Michael H. Carpenter, Timothy R. Bricker, Gregory R. Dick, CARPENTER LIPPS LLP, Columbus, Ohio, for Appellees. _________________

OPINION _________________

MURPHY, Circuit Judge. Dr. Flavia Pichiorri published many articles while working as a research scientist at The Ohio State University. Years after Pichiorri left Ohio State, though, a university committee found that she had committed research misconduct in some of these No. 24-3918 Pichiorri v. Burghes, et al. Page 2

articles. The committee later informed the relevant medical journals and her current employer of the misconduct. Pichiorri disagreed with the committee’s findings and believed that its disclosures to these third parties violated the Constitution. But the district court correctly found that sovereign immunity shielded some of the university defendants from this suit and that Pichiorri’s other due-process claims failed on the merits. We thus affirm the dismissal of Pichiorri’s complaint.

I

Because the district court dismissed Dr. Pichiorri’s complaint at the outset of her case, we must treat its well-pleaded factual allegations as true on appeal. See Blackwell v. Nocerini, 123 F.4th 479, 482, 486 (6th Cir. 2024). We thus describe the events using those allegations alone, while recognizing that Pichiorri has yet to support the allegations with concrete evidence. See id.

Pichiorri’s career has focused on research for cancer, including multiple myeloma and leukemia. Am. Compl., R.37, PageID 275–76. She has authored or coauthored over one hundred publications. Id., PageID 276. She has also “developed compounds and produced preclinical data” used in clinical trials. Id. And she has taught seminars and trained scientists. Id.

Pichiorri had a productive relationship with Ohio State for about a dozen years. She began as a “visiting Ph.D. student” in 2004. Id., PageID 275. After she obtained her doctorate from an Italian university in 2006, she became a researcher and later a research scientist in a lab run by Dr. Carlo Croce in Ohio State’s Department of Molecular Virology, Immunology and Medical Genetics. Id. She served in this research role until 2011 when she became an assistant professor in Ohio State’s College of Medicine. Id. Pichiorri left Ohio State (by all accounts on good terms) in August 2016. Id. She is now a professor at the City of Hope Medical Center in California. Id.

While working in Croce’s lab at Ohio State, Pichiorri coauthored several articles, including what her complaint calls Manuscripts 1, 2, and 5. Id., PageID 276–77. (Thankfully, we need not try to describe the manuscripts’ complex topics to resolve this appeal.) The cancer- research community “applauded” these articles. Id., PageID 277. And other scientists have No. 24-3918 Pichiorri v. Burghes, et al. Page 3

duplicated their findings, which “have never been refuted.” Id., PageID 277, 285. In fact, “more than seven hundred (700) researchers” have relied on the research findings over the years. Id., PageID 284. And Ohio State itself has used the findings to seek patents. Id., PageID 284–85.

After Pichiorri left Ohio State, however, unnamed individuals leveled “allegations of potential research misconduct” against Pichiorri for these manuscripts. Id., PageID 277. These individuals made the allegations between March 2017 and November 2018. Id. Ohio State responded by putting together a committee (“the College of Medicine Investigation Committee”) to investigate the alleged misconduct. Id., PageID 274, 277.

Because Ohio State accepts federal funds, the committee’s investigation needed to follow standards established by the Federal Office of Research Integrity. Id., PageID 278. These standards treat a researcher’s actions as “research misconduct” only if the actions rise to a certain level of malfeasance. Id. (citing 42 C.F.R. § 93.103(a)–(c) (2005)). So investigators may not treat an “honest error” as misconduct. Id., PageID 279. Although scientific articles often contain these types of “[h]onest mistakes,” their authors typically correct the errors through amendments. Id. And consistent with the federal standards, investigators do not typically treat the mistakes as misconduct. Id., PageID 278–79. Universities also must keep their investigations confidential under the federal standards. Id., PageID 278 (citing 42 C.F.R. § 93.108 (2005)).

Pichiorri cooperated with the committee’s investigation. Id., PageID 277–79. She recognized some honest errors in the manuscripts. Id., PageID 279. A figure in one manuscript had a “mistake in the legend,” and “images” in other manuscripts were allegedly false. Id. She thus submitted corrections and verified data to prove the validity of her conclusions despite the mistakes. Id. Pichiorri also placed the blame for the mistakes on her working conditions. Ohio State did not adequately “train[]” scientists and forced them “to work long days and nights” that made them prone to err. Id., PageID 280–81. Pichiorri placed further blame for the mistakes on her colleagues at Ohio State—who generated the underlying false data. Id., PageID 281. She exercised reasonable diligence when reviewing the data and merely failed to catch the errors. Id. No. 24-3918 Pichiorri v. Burghes, et al. Page 4

Ultimately, the committee issued a report in 2020. Id., PageID 283. The report found that Pichiorri (and another female scientist) had committed research misconduct. Id., PageID 279–81. It recommended that Ohio State bar Pichiorri from future employment with the university. Id., PageID 280. It also recommended that the relevant journals retract Manuscripts 1 and 2 and correct Manuscript 5. Id., PageID 282. On the other hand, the report did not find fault with Croce or any other male scientist who helped with the manuscripts. Id., PageID 279– 83.

According to the complaint, the committee departed from the Office of Research Integrity’s federal standards to make its findings. Id., PageID 280. The committee allegedly created its “own” unique research-misconduct rules for Pichiorri. Id. It did not require evidence that Pichiorri acted with an intent to defraud or even with a reckless disregard for the truth. Id. It also refused to disclose “exculpatory evidence” to Pichiorri that would have shown that she had not committed misconduct. Id. And it did not follow the “preponderance of the evidence” burden of proof that the federal standards require for a research-misconduct finding. Id., PageID 285.

The committee did not just disclose the report when it officially came out in 2020. It also re-sent the report to others (and repeated its misconduct findings) over the years. It alerted “prestigious journals” about the report as late as July and November 2022. Id., PageID 283.

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