Cytotheryx Inc v. Castle Creek Biosciences Inc & paragon Biosciences LLC

CourtCourt of Chancery of Delaware
DecidedNovember 10, 2025
Docket2023-1142-PAW
StatusPublished

This text of Cytotheryx Inc v. Castle Creek Biosciences Inc & paragon Biosciences LLC (Cytotheryx Inc v. Castle Creek Biosciences Inc & paragon Biosciences LLC) is published on Counsel Stack Legal Research, covering Court of Chancery of Delaware primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Cytotheryx Inc v. Castle Creek Biosciences Inc & paragon Biosciences LLC, (Del. Ct. App. 2025).

Opinion

IN THE COURT OF CHANCERY OF THE STATE OF DELAWARE

CYTOTHERYX, INC., ) ) Plaintiff, ) ) v. ) C.A. No. 2023-1142-PAW ) CASTLE CREEK BIOSCIENCES, ) INC. and PARAGON ) BIOSCIENCES, LLC, ) ) Defendants. ) ) CASTLE CREEK BIOSCIENCES, ) INC. and PARAGON ) BIOSCIENCES, LLC, ) ) Defendants, ) Counterclaimants, ) and Third-Party Plaintiffs, ) ) v. ) ) CYTOTHERYX, INC. and JOHN ) SWART, ) ) Plaintiff, Counter-Defendant, ) and Third-Party Defendant. ) )

Submitted: October 17, 2025 Decided: November 10, 2025

Upon Third-Party Defendant’s Motion to Dismiss; GRANTED, WITHOUT PREJUDICE. Upon Counterclaim Defendant’s Motion to Dismiss or Stay; DENIED.

MEMORANDUM OPINION AND ORDER Gary W. Lipkin, Esq.; Michelle C. Streifthau-Livizos, Esq.; and Courtland C. Merrill, Esq., of Saul Ewing LLP, Attorneys for Plaintiff and Counterclaim Defendant Cytotheryx, Inc.

Adam V. Orlacchio, Esq.; James G. Gorman III, Esq.; Gregory P. Ranzini, Esq.; and William J. Dorsey, Esq., of Blank Rome LLP, Attorneys for Defendants, Counterclaimants, and Third-Party Plaintiffs Castle Creek Biosciences, Inc. and Paragon Biosciences, LLC.

Marc S. Casarino, Esq.; and Katie Barksdale, Esq., of Kennedys CMK LLP, Attorneys for Counterclaim Defendant Cytotheryx, Inc. and Third-Party Defendant John Swart.

WINSTON, J.1

1 Sitting as a Vice Chancellor of the Court of Chancery by designation of the Chief Justice pursuant to In re: Designation of Actions Filed Pursuant to 8 Del. C. § 111 (Del. Nov. 4, 2024), most recently extended in the Fifth Amended Order dated May 30, 2025.

2 I. INTRODUCTION

This action stems from the sale of a Cytotheryx subsidiary to

Counterclaimants pursuant to a merger agreement. After the sale, Cytotheryx filed

a lawsuit alleging that Counterclaimants made misrepresentations in negotiations.

Then, Cytotheryx and its CEO issued an internet press release announcing the

lawsuit and making related statements about Counterclaimants. Counterclaimants

brought claims against Cyotheryx and Swart alleging their statements in the press

release were defamatory. Cytotheryx and Swart now move to dismiss those

Counterclaims.

The motions raise three primary questions:

First, which state’s law applies to the Counterclaims? The Court concludes

that Delaware law applies, because the Counterclaims are encompassed in the broad

choice-of-law provision the parties chose in the Merger Agreement. Contrary to

Cytotheryx’s and Swart’s contentions, the interests of Illinois, where one

Counterclaimant is headquartered, do not overcome this contractual choice.

Second, do the Counterclaims state claims for defamation under Delaware

law? At this early stage, the Court concludes that they do.

Third, does Delaware have personal jurisdiction over Swart, a non-resident?

The Court concludes that it does not. Delaware’s Officer Consent Statute provides

a statutory hook, but exercising jurisdiction over Swart would be inconsistent with

3 the Fourteenth Amendment’s due process clause. There are no allegations that Swart

made the statements in the internet press release while in Delaware or purposefully

directed his conduct here. Accordingly, Delaware lacks the requisite minimum

contacts to assert jurisdiction over Swart.

Cytotheryx’s motion to dismiss for failure to state a claim is DENIED, and

Swart’s motion to dismiss for lack of jurisdiction is GRANTED WITHOUT

PREJUDICE.

II. FACTUAL AND PROCEDURAL BACKGROUND2

A. THE PARTIES

Counterclaimant Castle Creek Biosciences, Inc. (“Castle Creek”) is a

Delaware Corporation with its principal place of business in Pennsylvania.3

Counterclaimant Paragon Biosciences, LLC (“Paragon” and, with Castle

Creek, “Counterclaimants”) is a Delaware LLC with its principal place of business

in Illinois.4

2 The facts are drawn from the Counterclaims and the documents incorporated therein. See D.I. 28, at 19-27 (hereinafter “Counterclaims”). The Court accepts as true the well-pled facts in the Counterclaims solely for purposes of the present motions to dismiss. The Court also references the Answer (see id. at 1-18 (hereinafter “Answer”)) and the Complaint in this action, but it does so solely for the purposes of discussing the context of the parties’ disputes. 3 Counterclaims ¶ 5. 4 Id. ¶ 6.

4 Counterclaim Defendant Cytotheryx, Inc. (“Cytotheryx”) is a Delaware

corporation with its principal place of business in Minnesota.5

Third-party defendant John Swart is the co-founder and CEO of Cytotheryx

and resides in Minnesota.6

B. THE UNDERLYING TRANSACTION AND THIS ACTION

On November 19, 2021, Castle Creek acquired novavita thera, Inc. from

Cytotheryx pursuant to a merger agreement (the “Merger Agreement”).7 As

payment, Castle Creek assigned shares in Castle Creek to Cytotheryx.8

Cytotheryx filed its first amended complaint in this action in January 2024

(the “FAC”). The FAC alleged that in the course of negotiating the transaction

Counterclaimants made misrepresentations about Cytotheryx’s ability to redeem the

Castle Creek shares it received as payment.9

C. THE ALLEGED DEFAMATORY STATEMENT

In addition to filing this action, Cytotheryx and Swart submitted a press

release to EIN Presswire.10 That press release—which was published in January

5 Id. ¶ 3. 6 Id. ¶ 4. 7 Answer ¶ 9. 8 Id. ¶ 10. 9 See Verified First Am. Compl. (D.I. 7) ¶¶ 4, 17-19 (hereinafter “FAC”). 10 Counterclaims ¶ 12.

5 2025, shortly after the FAC was filed—announced the lawsuit and made certain

related statements about Counterclaimants.11 In the portion relevant to the

Counterclaims, the press release quotes Swart as follows:

“We are shocked and disappointed in the failure of Castle Creek to meet its contractual obligations after the acquisition of novavita thera in 2021,” stated John Swart, Cytotheryx President and CEO. “The misrepresentations provided during the acquisition process by Castle Creek and Paragon Biosciences’ leadership teams, along with their refusal to provide payment under the contract terms, is not consistent with the actions of a financially stable company who adheres to their contractual obligations. We intend to pursue all available remedies under the law, to protect our investor’s interests and further enable our continuing research and development activities addressing liver failure.”12

Counterclaimants do not allege that Swart was physically present in Delaware

when he made these statements.

D. THE MERGER AGREEMENT’S CHOICE-OF-LAW PROVISION

The Merger Agreement governing the transaction contains a choice-of-law

provision. Specifically, Section 11.8(a) provides:

This Agreement and all claims and causes of action based upon, arising out of or in connection herewith shall be governed by, and construed in accordance with, the Laws of the State of Delaware, without regard to Laws that may be applicable under conflicts of laws principles (whether of the State of Delaware or any other jurisdiction) that

11 Id.; Counterclaims, Ex. C. 12 Counterclaims, Ex. C.

6 would cause the application of the Laws of any jurisdiction other than the State of Delaware.13

E. PROCEDURAL HISTORY

In the FAC, Cytotheryx brought claims for common law fraud and promissory

estoppel.14 The Court denied Counterclaimants’ motion to dismiss the FAC.15

Thereafter, Counterclaimants filed their Answer and Counterclaims for defamation

per se and defamation.16

Free access — add to your briefcase to read the full text and ask questions with AI

Related

International Shoe Co. v. Washington
326 U.S. 310 (Supreme Court, 1945)
Gertz v. Robert Welch, Inc.
418 U.S. 323 (Supreme Court, 1974)
Bertell Ollman v. Rowland Evans, Robert Novak
750 F.2d 970 (D.C. Circuit, 1984)
Ryan v. Gifford
935 A.2d 258 (Court of Chancery of Delaware, 2007)
Gloucester Holding Corp. v. U.S. Tape & Sticky Products, LLC
832 A.2d 116 (Court of Chancery of Delaware, 2003)
Barker v. Huang
610 A.2d 1341 (Supreme Court of Delaware, 1992)
Riley v. Moyed
529 A.2d 248 (Supreme Court of Delaware, 1987)
Aeroglobal Capital Management, LLC v. Cirrus Industries, Inc.
871 A.2d 428 (Supreme Court of Delaware, 2005)
Savor, Inc. v. FMR Corp.
812 A.2d 894 (Supreme Court of Delaware, 2002)
Lillis v. AT & T CORP.
904 A.2d 325 (Court of Chancery of Delaware, 2006)
Slawik v. News-Journal Co.
428 A.2d 15 (Supreme Court of Delaware, 1981)
Spence v. Funk
396 A.2d 967 (Supreme Court of Delaware, 1978)
In Re Tri-Star Pictures, Inc., Litigation
634 A.2d 319 (Supreme Court of Delaware, 1993)
Ramunno v. Cawley
705 A.2d 1029 (Supreme Court of Delaware, 1998)
Tuite v. Corbitt
866 N.E.2d 114 (Illinois Supreme Court, 2006)
Hazout v. Tsang Mun Ting
134 A.3d 274 (Supreme Court of Delaware, 2016)
Rice v. Simmons
2 Del. 417 (Supreme Court of Delaware, 1838)
Certain Underwriters at Lloyds, London v. Chemtura Cororporation
160 A.3d 457 (Supreme Court of Delaware, 2017)

Cite This Page — Counsel Stack

Bluebook (online)
Cytotheryx Inc v. Castle Creek Biosciences Inc & paragon Biosciences LLC, Counsel Stack Legal Research, https://law.counselstack.com/opinion/cytotheryx-inc-v-castle-creek-biosciences-inc-paragon-biosciences-llc-delch-2025.