AbbVie Inc. v. Adcentrx Therapeutics Inc.

CourtDistrict Court, S.D. California
DecidedFebruary 6, 2025
Docket3:23-cv-02290
StatusUnknown

This text of AbbVie Inc. v. Adcentrx Therapeutics Inc. (AbbVie Inc. v. Adcentrx Therapeutics Inc.) is published on Counsel Stack Legal Research, covering District Court, S.D. California primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
AbbVie Inc. v. Adcentrx Therapeutics Inc., (S.D. Cal. 2025).

Opinion

1 2 3 4 5 6 7 8 UNITED STATES DISTRICT COURT 9 SOUTHERN DISTRICT OF CALIFORNIA 10 11 ABBVIE INC., a Delaware corporation, Case No.: 23-CV-2290 TWR (DEB)

12 Plaintiff, ORDER (1) DENYING MOTION 13 v. TO COMPEL ARBITRATION, (2) DENYING AS MOOT 14 ADCENTRX THERAPEUTICS INC., MOTIONS TO STAY, AND a Delaware corporation; DONG JUN 15 (3) DENYING MOTIONS TO (Danny) LEE, an individual; and DOES DISMISS 16 1–10,

17 Defendants. (ECF Nos. 32, 33) 18

19 Presently before the Court are the Motion to Stay Pending Arbitration of Claims 20 Against Dr. Lee, or Alternative Motion to Dismiss (“Adcentrx Mot.,” ECF No. 32) filed 21 by Defendant Adcentrx Therapeutics Inc. (“Adcentrx”) and Motion to Compel Arbitration 22 and Stay Proceedings or, in the Alternative, to Dismiss the First Amended Complaint (“Lee 23 Mot.,” ECF No. 33) (together, the “Mots.”) filed by Defendant Dong Jun (Danny) Lee, as 24 well as the Opposition (“Opp’n,” ECF No. 35) filed by Plaintiff AbbVie, Inc. (“AbbVie”) 25 and Defendants’ joint Reply (“Reply,” ECF No. 36). The Court held a hearing on 26 December 19, 2024. (See generally ECF No. 37; see also ECF No. 38 (“Tr.”).) Upon 27 consideration of the Parties’ arguments, Plaintiff’s First Amended Complaint (“FAC,” ECF 28 No. 29), the record, and the applicable law, the Court DENIES Dr. Lee’s Motion to compel 1 AbbVie to arbitration, DENIES AS MOOT Dr. Lee’s and Adcentrx’s Motions to stay 2 pending arbitration of AbbVie’s claims against Dr. Lee, and DENIES Dr. Lee’s and 3 Adcentrx’s Motions to dismiss. 4 BACKGROUND 5 I. Factual Background1 6 A. AbbVie 7 “AbbVie is a global biopharmaceutical company headquartered in North Chicago, 8 Illinois.” (FAC ¶ 28.) “AbbVie was formed as an independent company in 2013, following 9 its separation from Abbott Laboratories.” (Id.) 10 “In 2015, AbbVie began the MTi (microtubule inhibitor) [antibody drug conjugate 11 (“ADC”)] program [(the “MTi ADC program”)], which focused on developing new ADCs 12 that incorporated microtubule inhibitors (“MTi”) as anti-cancer payloads/linker-drugs.” 13 (Id. ¶ 31.) “Unlike conventional chemotherapy, ADCs are targeted medicines that 14 selectively deliver anti-cancer payloads directly to cancer cells.” (Id. ¶ 30.) “ADCs 15 comprise (i) a monoclonal antibody that binds to a specific target (antigen) on the surface 16 of a cancer cell, plus (ii) an anti-cancer payload which is attached (conjugated) to the 17 antibody through (iii) a chemical linker.” (Id.) “The combination of the anti-cancer 18 payload and the linker is typically referred to as a ‘linker-drug.’” (Id. ¶ 2.) 19 “AbbVie’s MTi ADC program aimed to improve upon clinical stage and FDA- 20 approved MTi ADC products such as ADCETRIS®.” (Id. ¶ 31.) “These clinical stage and 21 FDA-approved products were predominantly based on the monomethyl auristatin E 22

23 1 For purposes of Defendants’ motions to dismiss, the Court “must accept as true all material 24 allegations in the complaint, as well as any reasonable inferences to be drawn from them,” and construe 25 AbbVie’s First Amended Complaint “in the light most favorable to the plaintiff.” See Broam v. Bogan, 320 F.3d 1023, 1028 (9th Cir. 2003). In resolving Dr. Lee’s motion to compel arbitration, however, 26 “district courts rely on the summary judgment standard of Rule 56 of the Federal Rules of Civil Procedure.” See Hansen v. LMB Mortg. Servs., Inc., 1 F.4th 667, 670 (9th Cir. 2021). Accordingly, “the 27 Court will consider the substance of evidence that would be admissible at trial.” See S.S. ex rel. Stern v. Peloton Interactive, Inc., 566 F. Supp. 3d 1019, 1044 (S.D. Cal. 2021) (citing Dinkins v. Schinzel, 362 F. 28 1 (“MMAE”) platform developed by Seattle Genetics (“SeaGen”).” (Id.) “AbbVie’s MTi 2 ADC program sought to develop novel payload designs and novel linker-drug designs not 3 based on the MMAE platform, to create highly effective, novel MTi ADCs.” (Id.) 4 In May 2015, AbbVie acquired Pharmacyclics, Inc., thereby becoming 5 Pharmacyclics LLC (“PCYC”), a wholly owned subsidiary of AbbVie. (See ECF No. 32- 6 1 (“Lee Decl.”) ¶ 5; ECF No. 32-2 (“Ex. 1”).) 7 B. Dr. Lee’s Employment with AbbVie 8 “AbbVie hired Lee as an ADC Chemist/Senior Scientist in February of 2015.” (FAC 9 ¶ 32). “As a condition of his employment with AbbVie, on February 2, 2015, Lee and 10 AbbVie executed an Employment Agreement.” (Id. ¶ 146; see also generally ECF No. 29- 11 5 (“Ex. E”).) This Employment Agreement included certain Inventions Assignment 12 Provisions providing that AbbVie owned all of Dr. Lee’s inventions during his employment 13 with AbbVie, (see FAC ¶¶ 149–51, 153, 204, 205; Ex. E ¶¶ 3–5), and Confidentiality 14 Provisions prohibiting Dr. Lee from disclosing or using AbbVie’s confidential information 15 for any purposes outside his employment with AbbVie. (See FAC ¶¶ 149, 152, 154, 215, 16 216; Ex. E ¶¶ 2, 3, 8.) 17 “Beginning in or around the fall of 2015, Lee worked on a team of chemists who 18 designed and synthesized payloads that were part of AbbVie’s MTi ADC program.” (FAC 19 ¶ 32.) “Thereafter, Lee quickly established himself as one of the key scientists in AbbVie’s 20 MTi ADC program, where Lee dedicated the bulk of his time from late 2015 until he left 21 for PCYC in January 2019.” (Id.) 22 Dr. “Lee’s role in AbbVie’s MTi ADC program was primarily to design, synthesize, 23 and evaluate AbbVie proprietary payload and linker-drug designs.” (Id. ¶ 33.) Dr. “Lee 24 tracked the payloads he designed and synthesized by using his initials: DJL (for Dong Jun 25 Lee),” i.e., Dr. “Lee designated the first payload he designed and synthesized while 26 employed at AbbVie as DJL-1, the second as DJL-2, and so on.” (See id. (emphasis in 27 original).) 28 / / / 1 Of particular significance to the instant action are payload designs DLJ-43 (also 2 ||referred to as ABBV-1), which Dr. Lee synthesized on November 8, 2016, and DLJ-51, 3 || which Dr. Lee synthesized no later than January 4, 2017. (See id. 4948, 49.) The structural 4 formulas of DJL-43/ABBV-1 and DLJ-51/ABBV-2 are depicted below: 5 ne ~ 6 ABBV - 1 - 4 OL Peps ry 9 □□ se || ABBV-2 hy A vt a Oo. Oo oO oO 12 13 id. 9 45.) “ABBV-1 has (4) an ortho-oriented anilino moiety at the C-terminus [green 14 || box], and (11) a tertiary amine-based hydrophilic moiety at the N-terminus [blue box].” (/d. 15 46.) “ABBV-2 has a (i) meta-oriented anilino moiety at the C-terminus [orange box], 16 |/and (ii) a tertiary amine-based hydrophilic moiety at the N-terminus [blue box].” (/d.) 17 ||“These compounds and their designs—including the orientation of the structural 18 ||components at the C- and N-terminus—are among the AbbVie payload trade secret 19 ||information.” (/d. 47.) “Documents created by Lee describing his work on DJL-43 and 20 || DJL-51 characterize these MTi-ADC payloads as ‘novel.’” (Ud. 4 50.) 21 C. Dr. Lee’s Employment with Pharmacyclics LLC 22 “In the second half of 2018, [Dr. Lee] became interested in potentially moving to 23 || California.” (Lee Decl. § 8.) Dr. Lee therefore explored the option of transferring from 24 || AbbVie, in Chicago, to PCYC, in Sunnyvale, (see id. J 9), and “communicated [his] desire 25 || to relocate [to California] via an internal transfer to [his] mentor Dr. Anthony Haight and 26 || to [his] manager Dr. Dennie Welch at AbbVie.” (See id. § 11.) 27 “On or around September 25, 2018, Dr. Jeff Zablocki, the recently appointed head 28 ||of medicinal chemistry at PCYC, visited the AbbVie Lake County facility . . . for an

1 || oncology portfolio review.” (See id. § 10.) Dr. Lee “met with Dr. Zablocki and told him 2 ||that [he] was interested in a potential transfer to the PCYC Sunnyvale office, and 3 || Dr.

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AbbVie Inc. v. Adcentrx Therapeutics Inc., Counsel Stack Legal Research, https://law.counselstack.com/opinion/abbvie-inc-v-adcentrx-therapeutics-inc-casd-2025.