World Nutrition Incorporated v. Advanced Enzymes USA

CourtDistrict Court, D. Arizona
DecidedFebruary 27, 2024
Docket2:19-cv-00265
StatusUnknown

This text of World Nutrition Incorporated v. Advanced Enzymes USA (World Nutrition Incorporated v. Advanced Enzymes USA) is published on Counsel Stack Legal Research, covering District Court, D. Arizona primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
World Nutrition Incorporated v. Advanced Enzymes USA, (D. Ariz. 2024).

Opinion

1 WO 2 3 4 5 6 IN THE UNITED STATES DISTRICT COURT 7 FOR THE DISTRICT OF ARIZONA

9 World Nutrition Incorporated, No. CV-19-00265-PHX-GMS

10 Plaintiff, ORDER

11 v.

12 Advanced Enzymes USA, et al.,

13 Defendants. 14 15 16 According to the stipulation of the parties, the Court held a bench trial from 17 December 12 through December 15, 2023. The Court hereby makes its Findings of Fact 18 and Conclusions of Law pursuant to Federal Rule of Civil Procedure 52. 19 FINDINGS OF FACT 20 Background 21 1. World Nutrition Incorporated (“WNI” or “Plaintiff”) sells enzyme products 22 to consumers. WNI is an Arizona corporation. 23 2. Mr. Ryuji Hirooka is the CEO, founder, and a shareholder of WNI. Mr. 24 Hirooka is not involved in the day-to-day operations of WNI. 25 3. Advanced Supplementary Technology Corporation (“AST” or “Defendant”) 26 sells enzyme products to consumers. AST is a California Corporation. 27 4. WNI and AST are competitors, each selling enzyme products in the same 28 markets directly to consumers, in health-food stores, and online. 1 5. Digestive enzyme products are designed to assist with digestion and are 2 absorbed in the stomach and intestines. 3 6. Systemic enzyme products are designed to work throughout the entire body 4 and should not be absorbed until they have passed through the stomach to be effective. 5 7. Systemic enzymes will degrade in gastric acid in the stomach. 6 8. Enteric coating protects enzymes from degrading in the stomach allowing 7 many, if not all, of the enzymes in a capsule to survive and be absorbed in the intestine. 8 9. AST sells four enzyme products relevant to this matter: Serracor–NK, 9 Excellacor, Serrapeptase, and Ultimate Metabolic Formula (“AST Products”). These 10 products are in a fine powder form, enclosed by a capsule. The capsule is not designed to 11 survive stomach acid; rather, the enteric protection is supplied in the process that granulizes 12 the powders before they are placed in the capsule. 13 10. The AST Products are systemic enzyme products. 14 11. WNI sells six enzyme products relevant to this matter: four Powder Products 15 and two Liquid Products. These products are enclosed by a capsule made of Zein. The 16 Zein capsule constitutes the enteric coating for the enzymes. 17 12. The Powder Products are Vitalzym Original Hybrid, Vitalzym Plus, 18 Vitalzym Cardio, and Vitalzym X. 19 13. The WNI Powder Products labels indicate they contain both systemic and 20 digestive enzymes. 21 14. The Liquid Products are Extra Strength and Vitalzym XE. 22 15. The WNI Liquid Products are systemic enzyme products. 23 16. The parties agree there is no liability for actions prior to 2016. 24 AST Products: Generally 25 17. AST uses enzyme blends in its AST Products. 26 18. AST purchases enzyme blends from Specialty Enzymes (“Specialty”). AST 27 is member of SEB Group, a family of companies including Specialty. 28 19. The AST Products are manufactured by Advanced Enzymes Technologies 1 (“AET”), which is also a member of the SEB Group. 2 20. Three of the AST Products were previously sold under different names. 3 a. Serrapeptase was formerly known as Peptizyme-SP. 4 b. Excellacor was formerly known as Excelzyme. 5 c. Ultimate Metabolic Formula was formerly known as Exclzyme-2AF. 6 21. The AST Products have been continuously advertised and sold in interstate 7 commerce since January 1, 2016. 8 AST Products: Serrapeptase 9 22. Since January 2016, the labels for all four AST Products state the product 10 contains enteric-coated serrapeptase. 11 23. AST advertisements repeatedly emphasized the efficacy of its enteric 12 coating: 13 a. “As a result of our experience and expertise, our entire line of enteric- 14 coated enzymes are able to reach the small intestine with higher activity for full 15 systemic enzyme therapy.” (P. Tr. Ex. 46 at AST0005090.) 16 b. “The enteric coating of our SEBkinase blend allows these sensitive 17 enzymes to survive the acidic conditions of the stomach, thus allowing them to pass 18 into the circulatory system maintaining high activity levels.” (P. Tr. Ex. 4 at 19 AST0002558.) 20 c. “The enteric coating in Peptizyme SP allows the enzymes to survive 21 the acidic conditions of the stomach, which increases absorption in the small 22 intestine, systemic activity and efficacy.” (P. Tr. Ex. 4 at AST0002567.) 23 24. As is stated above, AST does not use the same process as WNI to provide 24 enteric protection to its enzymes. Rather than providing the enteric coating through the 25 capsule in which they are sealed, AST mixes the polymer coating solution with the 26 serratiopeptidase and other enzymes inside of a Rapid Mixer Granulator (“RMG”) during 27 the granulation process. 28 25. An RMG operates by moving a propellor in a large tub filled with the 1 products to be placed inside the capsule. While the material is being moved, a blade chops 2 at a very high rate of speed, mixing the ingredients. 3 26. The polymer coating solution is added to the dry materials inside the RMG 4 and is thus granulized with the other powders. There is no other stage where enteric 5 protection is provided. 6 27. After the solution is mixed in, the material is vacuum dried and sifted into a 7 fine powder. 8 28. Scanning Electron Micrographs show that there is some enteric coverage of 9 the resulting powder, but there are also large gaps or holes in all the enteric material that 10 partially covers the granules. As a result, the enzymes in each of the granules is directly 11 exposed to stomach acid through the gaps and holes. Although the granulized substance is 12 then placed in capsules, those capsules do not provide any enteric protection for their 13 contents. 14 29. AST does not assert that its process designed to provide enteric protection 15 results in serrapeptase enzymes that are completely covered. It acknowledges that the AST 16 products have gaps or holes in the polymer that surrounds the serrapeptase. 17 30. Drs. David Savello and Jason Clevenger, agree that the AST Products lost 18 most of the serrapeptase they contained in the gastric acid designed to simulate the 19 stomach. Dr. Clevenger, AST’s expert, estimated that 73% of a capsule’s enzyme activity 20 would be lost through its exposure to stomach acid before it arrives at the intestines. 21 AST Products: Nattokinase 22 31. Serracor-NK contains an enzyme called nattokinase. 23 32. The nattokinase in Serracor-NK was not enteric coated from 2016 through 24 the summer of 2021. 25 33. Prior to 2016, AST advertised Serracor-NK as containing enteric-coated 26 serrapeptase and enteric-coated nattokinase. 27 34. Between 2016 and 2021, AST changed most of its advertisements for 28 Serracor-NK to state the product contained “enteric-coated serrapeptase and nattokinase.” 1 (See, e.g., P. Tr. Ex 46 at AST0005067). 2 35. The Frequently Asked Question webpage (“FAQ”) of the Serracor-NK 3 product represented that the nattokinase in Serracor-NK was enteric coated until June 2018. 4 36. The FAQ was the only instance showing AST claimed nattokinase was 5 enteric coated from 2016 until 2021. 6 37. AST does not dispute that the enteric-coating claim made on the FAQ was 7 false. 8 WNI Products: Generally 9 38. The WNI Products have been continuously advertised and sold since January 10 1, 2016, apart from Vitalzym Plus—which was discontinued in or around 2019. 11 WNI Products: Buffer Enteric Coating 12 39. As stipulated to by the parties, from August 1, 2016, through May 18, 2021, 13 WNI advertised on its website that the WNI Powder Products each contained buffer 14 enteric-coated serrapeptase. 15 40. WNI’s Powder Products did not contain buffer enteric-coated serrapeptase 16 as advertised. 17 41. Buffer enteric coating does not exist. 18 WNI Products: Labelling 19 42. WNI does not manufacture the enzyme products it sells. 20 43.

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World Nutrition Incorporated v. Advanced Enzymes USA, Counsel Stack Legal Research, https://law.counselstack.com/opinion/world-nutrition-incorporated-v-advanced-enzymes-usa-azd-2024.