National Research Development Corp. v. Varian Associates, Inc.

822 F. Supp. 1121, 28 U.S.P.Q. 2d (BNA) 1436, 1993 U.S. Dist. LEXIS 7534, 1993 WL 190497
CourtDistrict Court, D. New Jersey
DecidedMay 13, 1993
DocketCiv. A. 89-2459 (HAA)
StatusPublished
Cited by2 cases

This text of 822 F. Supp. 1121 (National Research Development Corp. v. Varian Associates, Inc.) is published on Counsel Stack Legal Research, covering District Court, D. New Jersey primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
National Research Development Corp. v. Varian Associates, Inc., 822 F. Supp. 1121, 28 U.S.P.Q. 2d (BNA) 1436, 1993 U.S. Dist. LEXIS 7534, 1993 WL 190497 (D.N.J. 1993).

Opinion

TRIAL OPINION

HAROLD A. ACKERMAN, District Judge.

In 1989, plaintiff the National Research Development Corporation (“NRDC” or “plaintiff’) brought this action against Varían Associates, Inc. (“Varían”) for infringement of a patent. Varian’s primary defense is their contention that, for a number of reasons, NRDC’s patent is invalid. All issues other than the validity and enforceability of the Hoult patent and Varian’s alleged infringement have been bifurcated and stayed for later separate trial.

Between February 9 and 23, 1993, this court held a bench trial. The following constitutes my findings of fact and conclusions of law. As is detailed below, I will deny NRDC’s claims against Varían because its patent is invalid pursuant to 35 U.S.C. § 102(b). Because of this finding, there is no longer any need for a subsequent trial.

I. Findings of Fact

A. The Background

This patent case involves the field of spectroscopy, the study and analysis of materials to determine their components and molecular structure: Nuclear magnetic resonance spectroscopy (“NMR”) is a particular form of spectroscopy that works by observing a material’s reaction to imposed radiation. NMR depends on the properties of nuclear magnetism and operates on relatively low radio frequencies.

NMR depends upon particular properties of atomic nuclei. Atomic nuclei are naturally *1122 electrically charged. This leads to a situation in which the nucleus essentially becomes a spinning magnet. In an NMR apparatus, a sample tube contains a number of atoms and molecules. Because in a sample there is an enormous number of spinning nuclei, there is no evidence of magnetism overall. However, when a sample is placed in an intense magnetic field, the nuclei will become aligned with the magnetic field — that is, they will begin to point north. As a result, the entire sample develops a small amount of magnetism.

If the experimenter then sends in a disturbance in the form of radio frequency radiation, the nuclei are first disturbed and then will return to their initial alignment. As they realign, they emit a short signal (a transient) which the experimenter can receive and analyze to determine information about the material.

To perform these experiments, an NMR apparatus normally consists of a large magnet, a material to be analyzed (often stored in a test tube), a radio-frequency pulse transmitter to excite a sample, and a radio-frequency receiver and detector, which will observe the response. Also, a device such as a computer memory is attached to the detector to store the recorded data.

NMR was independently discovered at Harvard' and Stanford Universities in 1945. For the first twenty years, spectrometers would transmit radio frequency radiation continuously, while varying the radio-frequency. Modern spectroscopy, though, uses a pulsed NMR method. In pulsed NMR, radiation is applied not continuously but in short pulses. As the nuclei react, a transient, temporary radio-frequency response will follow. The transient is then received by a probe, which is connected to a component of a receiver called a detector. The detector then produces a signal whose strength varies in precisely the same manner as the strength of the detected transient. The detected transient signals generally are printed or displayed as a spectrum of marks at frequencies characteristic of the material being analyzed.

In the mid-1960s, Yarian scientist Weston A. Anderson discovered a technology called Fourier transform NMR, a method of pulsed NMR in which the transmitter pulses excite the specimen by simultaneously producing a whole band of frequencies, covering the entire spectrum of possible frequencies. As the specimen responds to the various frequencies, a mathematical technique called Fourier transformation is used to translate the responses. It is universally felt that the Fourier transformation method greatly increased the capabilities of NMR technology and the sensitivities of NMR apparatus.

The patent at issue in this case involves a technology called quadrature phase detection (“QPD”). Initially, this means that the apparatus uses phase-sensitive detectors; that is, the transient signals received by the probe are combined with a reference signal in the receiver. In QPD, there are two phase-sensitive detectors, and the transient radio-frequency response splits into two parts. Each signal enters a “phase” and the resulting two signals are 90 degrees out of phase with each other (that is, they are in “relative phase quadrature”). The result, then, is two audio-frequency signals that come out correspondingly different, by an order of 90 degrees. The phase detectors differ only in the fact that their reference analyses are in relative phase quadrature with each other. QPD also expanded the capabilities of NMR machines.

In order to maximize results in NMR experiments, two further procedures need to be done.

The first involves strengthening the signal. When the transient signal is first received, it is very weak — that is, there is interference from random sources of noise and static— and therefore the signal is difficult to detect. However, if the experiment is done again and again, and if each time the signal is the same, the signal will continue to grow and become more audible. Also, when an experiment is done ten times, the signal grows by a factor of ten, but the unwanted noise grows only by a factor of three. Thus, when the experiment is repeated over and over again, and the results are added in the data storage, the signal to noise ratio improves, and the signal becomes much easier to detect. Typically, an experiment is repeated hundreds, thousands, or even a million times. This repeating of the experiment is termed “time averaging”.

*1123 Also performed on the detected signals is a mathematical manipulation called “data routing”. Data routing manipulates the resulting transient signals.

Despite the advances made by QPD, the technology originally had some problems. In order to be successful, a quadrature phase detector had to be perfectly balanced. That is, the machine had to be constructed properly so that the reference signals would be precisely 90 degrees out of phase. Slight deviations from these specifications could create problems in detection. If these problems were present — if, for example, the reference signals are not precisely 90 degrees out of phase — the removal of the unwanted frequencies is no longer perfect. Rather, each observed frequency is accompanied by a “ghost” frequency. The observing scientist cannot tell which frequency is real and which is a ghost. Sophisticated scientists, generally not involved in routine commercial NMR work, were able to solve the ghost problem by various mathematical manipulations.

B. The Hoult Patent

In the late 1960s and early 1970s, David Ian Hoult was completing his Ph.D at Oxford, under the supervision of Dr. (Sir) Rex Richards. During the course of his experiments, Dr. Hoult arrived at a means to solve the problems of “ghosts” without resorting to sophisticated manipulations of data.

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822 F. Supp. 1121, 28 U.S.P.Q. 2d (BNA) 1436, 1993 U.S. Dist. LEXIS 7534, 1993 WL 190497, Counsel Stack Legal Research, https://law.counselstack.com/opinion/national-research-development-corp-v-varian-associates-inc-njd-1993.