In re: Copaxone Antitrust Litigation

CourtDistrict Court, D. New Jersey
DecidedApril 13, 2026
Docket2:22-cv-01232
StatusUnknown

This text of In re: Copaxone Antitrust Litigation (In re: Copaxone Antitrust Litigation) is published on Counsel Stack Legal Research, covering District Court, D. New Jersey primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
In re: Copaxone Antitrust Litigation, (D.N.J. 2026).

Opinion

UNITED STATES DISTRICT COURT DISTRICT OF NEW JERSEY

In re: COPAXONE ANTITRUST

LITIGATION Master Docket No. 22-1232 (JXN)(JSA)

OPINION

NEALS, District Judge This is one of two pharmaceutical antitrust cases involving Copaxone, a drug used to treat multiple sclerosis.1 Before the Court is Special Master Faith S. Hochberg’s (“Special Master”) Report and Recommendation (“R&R”) recommending the Court grant Defendant Teva’s2 motion to dismiss in part the Complaint. (ECF No. 128.) Plaintiffs Walgreen Co., the Kroger Co., Albertsons Companies, Inc., and H-E-B, L.P. (“Retailers”) objected to the R&R (ECF No. 242), and Teva replied (ECF No. 252). The Court has carefully considered the parties’ submissions and decides this matter without oral argument pursuant to Federal Rule of Civil Procedure3 78 and Local Civil Rule 78.1. For the reasons set forth below, the Court ADOPTS the R&R (ECF No. 128).

1 For the related case, see Mylan Pharms. v. Teva Pharms. Indus. Ltd., No. 21-13087. 2 “Teva” collectively refers to Defendants Teva Pharmaceuticals, Ltd., Teva Pharmaceuticals USA, Inc., Teva Neuroscience, Inc., and Teva Sales & Marketing, Inc. 3 “Rule” or “Rules” hereinafter refer to the Federal Rules of Civil Procedure. I. BACKGROUND A. Drug Regulations To frame the antitrust issues in this case, the Court describes the relevant legal framework for approving and dispensing new drugs.

i. Approving New Drugs The Drug Price Competition and Patent Term Restoration Act of 1984, codified at 21 U.S.C. § 355 et seq., commonly referred to as the Hatch-Waxman Act, governs the approval of new drugs. A drug manufacturer “wishing to market a new prescription drug” must submit a New Drug Application (“NDA”) to the Food and Drug Administration (“FDA”) “and undergo a long, comprehensive, and costly testing process, after which, if successful, the manufacturer will receive marketing approval from the FDA.” F.T.C. v. Actavis, Inc., 570 U.S. 136, 142 (2013) (quoting 21 U.S.C. § 355(b)(1)). After the FDA approves a new drug whose active pharmaceutical ingredient has not been previously approved for any other drug, the manufacturer may exclusively make and sell that product for five years. 21 U.S.C. § 355(c)(3)(E)(ii).

“One of the goals of Hatch-Waxman is to increase competition between generic and brand- name drugs. To that end, the Act allows the manufacturers of generic drugs to obtain FDA approval without having to endure the gauntlet of procedures associated with NDAs.” In re Wellbutrin XL Antitrust Litig. Indirect Purchaser Class, 868 F.3d 132, 143 (3d Cir. 2017). So, after the FDA approves a brand-name drug, Hatch-Waxman permits a generic drug manufacturer to submit an Abbreviated New Drug Application (“ANDA”) “specifying that the generic has the ‘same active ingredients as,’ and is ‘biologically equivalent’ to, the already-approved brand-name drug.” Actavis, 570 U.S. at 142 (quoting Caraco Pharm. Lab’ys, Ltd. v. Novo Nordisk A/S, 566 U.S. 399, 404 (2012)). Filing an ANDA allows “the generic to piggy-back” on the brand-name drug’s prior approval, eliminating the need to undergo the same “costly and time-consuming studies” as the brand-name drug. Id. (quoting Eli Lilly & Co. v. Medtronic, Inc., 496 U.S. 661, 676 (1990)). Hatch-Waxman also “sets forth special procedures for identifying, and resolving, related patent disputes” between NDAs and ANDAs. Id. at 143. The Act requires the “brand-name

manufacturer to list in its [NDA] the ‘number and the expiration date’ of any relevant patent.” Id. (quoting 21 U.S.C. § 355(b)(1)). The FDA then publishes the approved NDA, along with its corresponding patent numbers and expiration dates, “in a fat, brightly hued volume called the Orange Book (less colorfully but more officially denominated Approved Drug Products with Therapeutic Equivalence Evaluations).” Caraco Pharm., 566 U.S. at 405–06. Because the FDA “cannot authorize a generic drug that would infringe a patent,” a generic drug company filing an ANDA “must assure the FDA that its proposed generic drug will not infringe the [brand drug’s] patents.” Id. The generic manufacturer “can provide this assurance in one of several ways.” Actavis, 570 U.S. at 143. One option, relevant here, is called a “Paragraph IV Certification,” wherein the generic manufacturer certifies that “any listed, relevant patent ‘is

invalid or will not be infringed by the manufacture, use, or sale’ of the drug described in the [ANDA].” Id. (quoting 21 U.S.C. § 355(j)(2)(A)(vii)). A Paragraph IV Certification “automatically counts as patent infringement.” Id. “If the brand-name patentee brings an infringement suit within [forty-five] days, the FDA then must withhold approving the generic, usually for a [thirty]–month period, while the parties litigate patent validity (or infringement) in court.” Id.; see also 21 U.S.C. § 355(j)(5)(B)(iii). “If the courts decide the matter within that period, the FDA follows that determination; if they do not, the FDA may go forward and give approval to market the generic product.” Actavis, 570 U.S. at 143 (citing 21 U.S.C. § 355(j)(5)(B)(iii)). ii. Dispensing New Drugs The Complaint notes that many states have “automatic substitution” laws. (Compl. ¶ 74, ECF No. 2.) Automatic substitution laws require pharmacies to substitute generic drugs for brand drugs “even if the prescription specifies the brand drug.” (Id.) The Retailers, however, allege

automatic substitution cannot occur where a prescription for a brand drug states, “Dispense as Written” (“DAW”). (Id. ¶ 157.) B. Copaxone Teva makes and sells Copaxone, an injectable drug used to treat multiple sclerosis. (Id. ¶ 87.) The FDA first approved Copaxone in a 20mg vial in December 1996. (Id. ¶ 88.) In its initial form, users would inject themselves with Copaxone. (See id.) The FDA approved syringes pre- filled with 20mg of Copaxone for daily injectable use on February 12, 2002. (Id.) The patents for 20mg Copaxone expired in May 2014. (Id. ¶¶ 103.) Sandoz, a pharmaceutical company, filed an ANDA for generic 20mg Copaxone in December 2007 (id. ¶ 92), which the FDA approved in April 2015. (Id. ¶ 94).

In 2013, Teva filed a supplemental NDA (“sNDA”) for 40mg Copaxone in a pre-filled syringe, to be injected three times a week, which the FDA approved in January 2014. (Id. ¶ 89.) The legal exclusivity for 40mg Copaxone expired on January 28, 2017. (See id. ¶¶ 89, 131.) Mylan, another pharmaceutical company, filed ANDAs for generic 20mg Copaxone in June 2009 (id. ¶ 97), and generic 40mg Copaxone on February 12, 2014. (Id. ¶ 98). The FDA approved both ANDAs on October 3, 2017. (Id. ¶ 99.) Mylan launched its generic 20mg and 40mg Copaxone the next day. (Id. ¶ 100.) C. Pharmacy Benefit Managers Pharmacy Benefit Managers (“PBMs”) are middlemen between health insurance companies and consumers. (Id. ¶ 81.) They negotiate drug prices with manufacturers and reimbursements with pharmacies. (Id. ¶ 82.) Many PBMs also own specialty pharmacies. (Id.)

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In re: Copaxone Antitrust Litigation, Counsel Stack Legal Research, https://law.counselstack.com/opinion/in-re-copaxone-antitrust-litigation-njd-2026.