I-Mab Biopharma v. Inhibrx, Inc.

District Court, D. Delaware·Decided October 17, 2024·No. 1:22-cv-00276·Unknown

Opinion

IN THE UNITED STATES DISTRICT COURT FOR THE DISTRICT OF DELAWARE

I-MAB BIOPHARMA, ) ) Plaintiff, ) ) v. ) Civil Action No. 22-276-CJB ) INHIBRX, INC. and BRENDAN ) ECKELMAN, ) ) Defendants. ) MEMORANDUM ORDER

In this case, Plaintiff I-Mab Biopharma (“I-Mab” or “Plaintiff”) brings trade secret misappropriation claims against Defendants Inhibrx, Inc. (“Inhibrx”) and Brendan Eckelman (“Dr. Eckelman” and collectively with Inhibrx, “Defendants”). Presently pending before the Court is Plaintiff’s motion to exclude certain opinions offered by Defendants’ damages expert Dr. Richard Manning (the “Motion”). (D.I. 343) I-Mab opposes the Motion. For the reasons set forth below, the Motion is GRANTED-IN-PART and DENIED-IN-PART (with the exception of the portion of the Motion relating to Dr. Manning’s alternative damages theory, which the Court will take up when it considers Plaintiff’s motion to exclude the opinions of Dr. Roland Newman, (D.I. 344)).1 I. BACKGROUND I-Mab commenced this action on March 1, 2022. (D.I. 2) The operative First Amended Complaint (“FAC”), filed on May 12, 2022, contains two causes of action, both for trade secret misappropriation against both Defendants: Count I, which alleges a violation of the federal

1 The parties have jointly consented to the Court’s jurisdiction to conduct all proceedings in this case, including trial, the entry of final judgment and all post-trial proceedings. (D.I. 89) Defend Trade Secrets Act (“DTSA”), and Count II, which alleges a violation of the Delaware Uniform Trade Secrets Act. (D.I. 49 at ¶¶ 175-201) Plaintiff asserts that Defendants misappropriated nine trade secrets (that correspond to molecules designed to treat cancer) that are referred to herein as Trade Secret 1, Trade Secret 2, Trade Secret 4, Trade Secret 5, Trade

Secret 6, Trade Secret 7, Trade Secret 8, Trade Secret 9 and Trade Secret 10. (See, e.g., id. at ¶¶ 50, 59-70; D.I. 337, ex. 6 at 7-23)2 Plaintiff filed the instant Motion on June 14, 2024. (See D.I. 331) The Motion was fully briefed as of July 24, 2024. (D.I. 383) Trial is set for October 28, 2024. (D.I. 301 at 2) The Court here writes primarily for the parties, and so any additional facts relevant to this Memorandum Order will be discussed in Section III below. II. STANDARD OF REVIEW The Court has frequently set out the relevant standard of review for assessing a motion, like this one, filed pursuant to Federal Rule of Evidence 702 (“Rule 702”) and Daubert v. Merrell Dow Pharms, Inc., 509 U.S. 579 (1993). One such instance came in Integra LifeScis.

Corp. v. HyperBranch Med. Tech., Inc., Civil Action No. 15-819-LPS-CJB, 2018 WL 1785033, at *1-2 (D. Del. Apr. 4, 2018). The Court incorporates by reference those legal standards set out in Integra, and will follow them herein. To the extent that additional related legal principles regarding Rule 702 and Daubert are relevant, the Court will set those out in Section III. III. DISCUSSION With its Motion, Plaintiff seeks to exclude three categories of Dr. Manning’s opinions. The Court will take up two of these categories below, and will reserve decision on the third

2 Plaintiff has dropped Trade Secret 3 from the case. (D.I. 367 at 7 n.6; D.I. 408 at 15 n.14) 2 category until it resolves Plaintiff’s motion to exclude the opinions of Dr. Newman (the “Newman Daubert motion”).3 A. Dr. Manning’s reliance on the “Book of Wisdom” doctrine Under the reasonable royalty framework of damages permitted under the DTSA, parties

rely upon a hypothetical negotiation analysis to “attempt to ascertain the royalty upon which the parties would have agreed had they successfully negotiated an agreement just before [misappropriation] began.” Aqua Shield v. Inter Pool Cover Team, 774 F.3d 766, 770 (Fed. Cir. 2014) (brackets and internal quotation marks and citation omitted);4 see also Vt. Microsys., Inc. v. Autodesk, Inc., 88 F.3d 142, 151 (2d Cir. 1996) (“A reasonable royalty award attempts to measure a hypothetically agreed value of what the defendant wrongfully obtained from the plaintiff. By means of a ‘suppositious meeting’ between the parties, the court calculates what the parties would have agreed to as a fair licensing price at the time that the misappropriation occurred.”). The hypothetical negotiation must attempt to “recreate the ex ante licensing negotiation scenario and to describe the resulting agreement.” Lucent Techs., Inc. v. Gateway,

Inc., 580 F.3d 1301, 1325 (Fed. Cir. 2009). However, the analysis “permits and often requires a

3 One of Plaintiff’s arguments is that Dr. Manning’s alternative damages theory should be excluded because Dr. Manning relied only on a conversation with Dr. Newman in support. (D.I. 331 at 11-12) Plaintiff also seeks to exclude Dr. Newman’s related opinion in the Newman Daubert motion. (Id. at 17-20) For efficiency’s sake, the Court will therefore take up this portion of the Motion at the same time that it assesses the Newman Daubert motion.

4 One court has noted that “caselaw on how to determine a reasonable royalty for misappropriated trade secrets . . . is scarce” and therefore parties in trade secret misappropriation cases “understandably rely largely on well-trodden caselaw from the patent infringement context[.]” Motorola Sols., Inc. v. Hytera Commc’ns Corp., Case No. 1:17-cv-01973, 2021 WL 6690279, at *2 (N.D. Ill. Dec. 14, 2021). At times herein, then, the Court will cite to a discussion of the relevant law in this area that is drawn from opinions in patent litigation cases, as opposed to trade secret misappropriation cases. 3 court to look to events and facts that occurred thereafter and that could not have been known to or predicted by the hypothesized negotiators.” Fromson v. W. Litho Plate & Supply Co., 853 F.2d 1568, 1575 (Fed. Cir. 1988), overruled on other grounds by Knorr-Bremse Systeme Fuer Nutzfahrzeuge GmbH v. Dana Corp., 383 F.3d 1337 (Fed. Cir. 2004). Facts that post-date the

hypothetical negotiation may sometimes be relied upon in a reasonable royalty analysis as part of the “Book of Wisdom.” Cirba Inc. v. VMware, Inc., Civil Action No. 19-742-LPS, 2021 WL 7209447, at *2 (D. Del. Dec. 14, 2021); see also Sinclair Refin. Co. v. Jenkins Petroleum Process Co., 289 U.S. 689, 698 (1933) (“[A] different situation is presented if years have gone by before the evidence is offered. Experience is then available to correct uncertain prophecy. Here is a book of wisdom that courts may not neglect.”). Plaintiff asserts that Dr. Manning’s opinions based on events that occurred years after the date of the hypothetical negotiation in November 2021 should be excluded because he improperly utilizes the Book of Wisdom. (D.I. 331 at 13-15; D.I. 383 at 8-10) According to Plaintiff, while the Book of Wisdom would permit an expert to rely on post-negotiation evidence

to demonstrate a party’s actual state of mind in November 2021, Dr. Manning does not rely on such evidence in this way—and instead improperly uses it to replace the inquiry into what the parties would have anticipated. (D.I. 331 at 13; D.I. 383 at 8) Plaintiff asserts that Dr.

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I-Mab Biopharma v. Inhibrx, Inc., (D. Del. 2024).

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