GENENTECH, INC. v. SANDOZ, INC.

CourtDistrict Court, D. New Jersey
DecidedJanuary 3, 2025
Docket2:23-cv-04085
StatusUnknown

This text of GENENTECH, INC. v. SANDOZ, INC. (GENENTECH, INC. v. SANDOZ, INC.) is published on Counsel Stack Legal Research, covering District Court, D. New Jersey primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
GENENTECH, INC. v. SANDOZ, INC., (D.N.J. 2025).

Opinion

Not for Publication

UNITED STATES DISTRICT COURT DISTRICT OF NEW JERSEY

GENENTECH, INC. and HOFFMANN-LA ROCHE INC., Civil Action No. 23-4085 (ES) (LDW) Plaintiffs, OPINION v.

SANDOZ, INC. and LEK PHARMACEUTICALS D.D.,

Defendants.

SALAS, DISTRICT JUDGE Before the Court is Defendants’1 appeal of the March 5, 2024 Opinion and Order of the Honorable Leda D. Wettre, U.S.M.J., denying Defendants’ motion to transfer this matter to the United States District Court, District of Delaware (D.E. No. 56 (“March 5 Opinion” or “Mar. 5 Op.”)). (D.E. No. 57 (“Appeal”); see also D.E. No. 57-1 (“Mov. Br.”)). Plaintiffs opposed (D.E. No. 58 (“Opp. Br.”) and Defendants replied (D.E. No. 60 (“Reply Br.”)). The Court has considered the parties’ submissions and decides this Appeal without oral argument. See Fed. R. Civ. P. 78(b); see also L. Civ. R. 78.1(b). For the reasons below, the Court AFFIRMS the March 5 Opinion and DENIES Defendants’ Appeal. I. BACKGROUND AND PROCEDURAL HISTORY The Court briefly recites the factual background and procedural history necessary for resolution of the instant Appeal. On July 31, 2023, Plaintiffs initiated this action alleging one

1 Defendants are Sandoz Inc. (“Sandoz”) and Lek Pharmaceuticals D.D. (“Lek,” together with Sandoz, “Defendants”). Plaintiffs are Genentech, Inc. (“Genentech”) and Hoffman-La Roche Inc. (“HLR,” together with Genentech, “Plaintiffs”). count of infringement of United States Patent No. 10,188,637 (the “’637 Patent”), entitled “Granulate Formulation of 5-Methyl-1-Phenyl-2-(1H)-Pyridone and Method of Making the Same.” (D.E. No. 1 (“Complaint” or “Compl.”) ¶¶ 15 & 44–56). The ’637 Patent covers a novel tablet formulation of pirfenidone, a drug approved for treatment of idiopathic pulmonary fibrosis

(“IPF”). (Id. ¶ 1). On January 29, 2019, the United States Patent and Trademark Office issued the ’637 Patent, which expires on or about March 28, 2037. (Id. ¶ 15). Genentech holds approved New Drug Applications (“NDAs”) for pirfenidone capsules and tablets, each 267 mg, as well as 801 mg tablets, all of which are prescribed and sold under the Esbriet® trademark to treat IPF and are covered by the ’637 Patent. (Id. ¶ 3). Genentech is a pharmaceutical company incorporated in Delaware and operates its principal place of business in San Francisco, California. (Id. ¶ 24). HLR is incorporated in, and operates its principal place of business in, New Jersey. (Id. ¶ 26). Sandoz is incorporated in Delaware and operates its principal place of business in New Jersey. (Id. ¶ 27). Lek is incorporated in, and operates its principal place of business in, Slovenia. (Id. ¶ 28). Lek represents that it is a

subsidiary of Sandoz and Novartis. (Id. ¶¶ 28–29). As alleged in the Complaint, HLR owns the ’637 patent and Genentech is the exclusive licensee. (Id. ¶¶ 16, 24 & 26). Plaintiffs assert Genentech “hold[s] all substantial rights to the ’637 patent, including the rights to enforce the ’637 patent and to seek damages for past, current, and future infringement thereof.” (Id. ¶ 16). As alleged in the Complaint, in or around 2019, Defendants and other pharmaceutical companies submitted NDAs seeking approval to market generic Esbriet® tablets and capsules. (Id. ¶ 17). Genentech previously sued Defendants as well as other pharmaceutical companies in the District of Delaware, seeking remedies under the Hatch-Waxman Act for alleged patent infringement of twenty allegedly “materially different patents.” (Id.; see D.E. No. 55 (Jan. 12, 2024 Oral Argument Transcript (“OA Tr.”)) at 7:10–11 & 22:7–9). The District of Delaware consolidated the prior patent infringement actions in Genentech, Inc. v. Laurus Labs, Ltd. et al., No. 19-0078 (D. Del. Jan. 14, 2019) (the “Pirfenidone ANDA Litigation”)). (Compl. ¶ 17). As recognized by Defendants, the ’637 Patent “is from a different family [of patents] than the patents

that went to trial in Delaware.” (OA Tr. at 23:12–14; id. at 24:1–4 (admitting that the ’637 Patent “bears no family relationship with the patents that were asserted in Delaware”)). The ’637 Patent issued during the pendency of the Pirfenidone ANDA Litigation. (Compl. ¶ 18). Plaintiffs maintain the ’637 Patent “is unrelated to the patents at issue in the Pirfenidone ANDA Litigation and its claims are materially different and patentably distinct from the claims asserted in that case.” (Id.). In December 2020, Defendants sent Genentech a Paragraph IV Certification pursuant to 21 U.S.C. § 505(j)(2)(B)(iv), in which they maintained that the claims of the ’637 Patent were invalid and thus not infringed. (Id. ¶ 19). The other companies involved in the Pirfenidone ANDA Litigation were dismissed on consent between 2019 and 2021. (Id. ¶ 20). No generics launched during or immediately after

their dismissal. (Id.). On March 22, 2022, the Honorable Richard G. Andrews, U.S.D.J., issued a trial opinion as to the remaining defendants, Sandoz and Lek. Genentech, Inc. v. Sandoz, Inc., 592 F. Supp. 3d 355 (D. Del. 2022). In May 2022, after they “prevailed at the district court in the Pirfenidone ANDA Litigation,” Defendants launched their generic versions of pirfenidone tablets that allegedly infringe on the ’637 Patent. (Compl. ¶¶ 1 & 20). On December 22, 2022, Defendants also prevailed on appeal to the Federal Circuit. See Genentech, Inc. v. Sandoz Inc., 55 F.4th 1368 (Fed. Cir. 2022). According to Plaintiffs, Defendants launched their generic pirfenidone tablets (267 mg and 801 mg) notwithstanding their knowledge of the ’637 Patent’s listing in the Food and Drug Administration’s (“FDA”) Approved Drug Products with Therapeutic Equivalence Evaluations (the “Orange Book”) for Esbriet® tablets. (Compl. ¶¶ 1 & 20). Despite Plaintiffs’ request for monetary damages in the “hundreds of millions—if not billions—of dollars in lost profits,” they have not sought an injunction to remove any allegedly infringing generic pirfenidone products from store shelves. (Id. ¶ 1).

On October 20, 2023, Defendants filed a motion to transfer this action to the District of Delaware based on the Pirfenidone ANDA Litigation, in which Judge Andrews presided. (D.E. No. 47; D.E. No. 47-25 (“Initial Mov. Br.”) at 1). On January 12, 2024, Judge Wettre held oral argument on Defendants’ motion to transfer. (D.E. Nos. 53 & 55). On March 5, 2024, Judge Wettre denied Defendants’ motion to transfer. (Mar. 5 Op.). On March 19, 2024, Defendants appealed the March 5 Opinion to the District Judge. (D.E. No. 57). The Appeal is fully briefed. (Mov. Br.; Opp. Br.; Reply Br.). On September 4, 2024, this matter was reassigned to the Undersigned. (D.E. No. 88). II. LEGAL STANDARD

A. Appeal of Magistrate Judge Decisions

“Appeals from the orders of magistrate judges are governed by Local Civil Rule 72.1(c).” McDonough v. Horizon Blue Cross Blue Shield of N.J., Inc., No. 09-0571, 2013 WL 322595, at *2 (D.N.J. Jan. 22, 2013). The standard of review of a magistrate judge’s decision depends on whether the magistrate judge addressed a dispositive or non-dispositive issue. Id. On appeal of a non-dispositive order, such as the March 5 Opinion entered by Judge Wettre in this case, a district court may modify or set aside the magistrate judge’s decision if it was clearly erroneous or contrary to law. Eisai Co., Ltd. v. Teva Pharms. USA, Inc., 629 F. Supp. 2d 416, 424 (D.N.J. 2009); Fed. R. Civ. P. 72(a); L. Civ. R.

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