Apuzzo v. Secretary of Health and Human Services

CourtUnited States Court of Federal Claims
DecidedApril 2, 2025
Docket17-1915
StatusPublished

This text of Apuzzo v. Secretary of Health and Human Services (Apuzzo v. Secretary of Health and Human Services) is published on Counsel Stack Legal Research, covering United States Court of Federal Claims primary law. Counsel Stack provides free access to over 12 million legal documents including statutes, case law, regulations, and constitutions.

Bluebook
Apuzzo v. Secretary of Health and Human Services, (uscfc 2025).

Opinion

In the United States Court of Federal Claims No. 17-1915V (Filed Under Seal: March 18, 2025) 1 Reissued: April 2, 2025

) ANGELA APUZZO, ) ) Petitioner, ) ) v. ) ) SECRETARY OF HEALTH AND ) HUMAN SERVICES, ) ) Respondent. ) )

OPINION & ORDER

Meredith Daniels, Conway Homer, P.C., Boston, MA, for petitioner. Also represented by Ronald Craig Homer.

Debra A. Filteau Begley, Vaccine/Torts Branch, Civil Division, United States Department of Justice, Washington, D.C., for respondent.

SMITH, Senior Judge

This case concerns how the Office of Special Masters at the United States Court of Federal Claims must evaluate competing expert opinions in vaccine injury cases. Special Master Daniel T. Horner denied compensation to petitioner, Ms. Angela Apuzzo, because he concluded—after reviewing the respective expert reports submitted by both respondent, the Secretary of Health and Human Services, and Ms. Apuzzo—that she suffers from Sjögren’s Syndrome, rather than her alleged acute-onset chronic inflammatory demyelinating polyneuropathy (“CIDP”), caused by an influenza vaccination on September 17, 2015. See generally Apuzzo v. Sec’y of Health & Hum. Servs., No. 17-1915V, 2024 WL 4534200 (Off. Spec. Mstr. Sept. 20, 2024). To Ms. Apuzzo, the Special Master’s conclusion violates binding precedent instructing special masters not to “conduct a differential diagnosis” by choosing one expert’s opinion over another, “or over a combination of” expert and treating physicians’ opinions. See generally Petitioner’s Memorandum in Support of Her Motion for Review the Special Master’s September 20, 2024, Decision, ECF No. 166 [hereinafter Pet’r’s Mot.].

1 This opinion was issued under seal on March 18, 2025. The parties were given an opportunity to propose redactions before public release, but no such proposals were made. The Court disagrees. Special Master Horner was required to evaluate the reliability of the parties’ expert reports because, in contrast to respondent’s experts, neither Ms. Apuzzo’s treating physicians nor her experts agreed on the proper diagnosis for her symptoms. See, e.g., Pafford v. Sec’y of Health & Hum. Servs., 451 F.3d 1352, 1356 (Fed. Cir. 2006) (holding that it is not arbitrary and capricious for a special master to conclude that a claimant did not prove causation by reviewing and comparing the expert evidentiary record); Lombardi v. Sec’y of Health & Hum. Servs., 656 F.3d 1343, 1353–54 (Fed. Cir. 2011) (same). The Special Master’s decision is therefore affirmed.

I

On September 17, 2015, Ms. Apuzzo received the influenza vaccination at issue. Apuzzo, 2024 WL 4534200, at *4. On October 5, 2015, Ms. Apuzzo was reviewed by emergency health professionals after she complained of four days of numbness and tingling in her hands, feet, and the right side of her face. Id. The emergency health professionals “suspected” hypothyroidism but suggested that she follow up with a neurologist due to her mild peripheral neuropathy. Id. On October 28, 2015, Ms. Apuzzo met with Dr. Bronfin, 2 a neurologist. Id. “Dr. Bronfin diagnosed Guillain- Barré Syndrome . . . and peripheral demyelinating neuropathy.” Id. (acronym omitted). That same day, based on Dr. Bronfin’s diagnosis, Ms. Apuzzo returned to the emergency health professionals and was transferred to inpatient neurologic observation at a hospital. Id. During her hospitalization, Ms. Apuzzo’s blood test results “were significant for positive antinuclear antibodies . . . and elevated anti-Sjögren's syndrome- related antigen A antibodies,” but no tests definitively determined that she suffered from Guillain-Barré Syndrome. Id. Ms. Apuzzo then had a rheumatological consultation to address possible Sjögren's Syndrome. Id. “Given her history of arthritis and positive Sjögren's Syndrome antibodies, as well as the fact [Guillain-Barré Syndrome] was not definitively diagnosed, rheumatology considered Sjögren's [S]yndrome as a possible explanation for petitioner's peripheral neuropathy and recommended continuing to treat for [Guillain-Barré Syndrome] while monitoring for Sjögren's [S]yndrome.” Id. The consultant recommended that Ms. Apuzzo follow-up to determine if Sjögren's Syndrome was main cause of her symptoms. Id. On November 3, 2015, Ms. Apuzzo was discharged from the hospital with a diagnosis of Guillain- Barré Syndrome and peripheral demyelinating neuropathy. Id.

On November 17, 2025, Ms. Apuzzo returned to Dr. Bronfin because she was still experiencing numbness, tingling, and a tremor. Id. at *5. After reviewing Ms. Apuzzo, “Dr. Bronfin maintained his diagnoses of [Guillain-Barré Syndrome] and peripheral demyelinating neuropathy, but also added Sjögren's [S]yndrome to his assessment.” Id. Dr. Bronfin then prescribed a series of treatments that tended to cause improvements in Ms. Apuzzo’s condition. Id.

2 Special Master Horner’s decision only uses last names for certain physicians. Where a first name is used, the Court does so as well.

-2- On January 19, 2016, Ms. Apuzzo was evaluated by a rheumatologist, Dr. Lee. Id. Finding Ms. Apuzzo to be positive for Sjögren's Syndrome antibodies, Dr. Lee determined that her condition could be presented with peripheral neuropathy, but decided to wait on performing more tests to confirm this diagnosis, given Ms. Apuzzo’s apparent improvement in response to Dr. Bronfin’s treatment plan. Id. Ms. Apuzzo was to contact Dr. Lee again if her condition stopped improving or became worse. Id.

On February 1, 2016, Ms. Apuzzo returned to Dr. Bronfin, complaining of increased weakness and shortness of breath. Id. He found that Ms. Apuzzo was neurologically stable but refered her to emergency health services due to her shortness of breath. Id. The hospital conducted a series of tests, which ruled out Guillain-Barré Syndrome, and now offered CIDP as a possible cause for Ms. Apuzzo’s symptoms. Id. On March 8, 2016, Ms. Apuzzo once again returned to Dr. Bronfin due to her condition “not improving,” and Ms. Apuzzo continued her treatment plan under Dr. Bronfin’s unchanged diagnosis of Sjögren's Syndrome, Guillain-Barré Syndrome, and peripheral demyelinating neuropathy. Id. (internal quotation marks omitted).

Between March 21, 2016, and August 22, 2017, Ms. Apuzzo saw at least four different specialists. Id. at *6–7. On March 21, 2016, Ms. Apuzzo visited Dr. Busono, a neuromuscular specialist, who, after diagnostic testing, began to “doubt the diagnosis of CIDP,” and Dr. Bronfin’s treatment plan was discontinued as a result. Id. at *6 (internal quotation marks omitted). In August of 2016, Ms. Apuzzo consulted Dr. Kapur, a neurologist, who restarted Dr. Bronfin’s treatment with additional treatments prescribed, and Ms. Apuzzo was to return to Dr. Kapur once he received her medical records. Id. On October 4, 2016, Ms. Apuzzo visited Dr. Kapur for a second time. Id. During the visit, Dr. Kapur noted that Ms. Apuzzo still had Sjögren's Syndrome antibodies, so her symptoms “could be consistent with either CIDP or small fiber neuropathy related to Sjögren's [S]yndrome,” and recommended that Ms. Apuzzo continue her already prescribed treatment plan. Id. On February 3, 2017, Ms. Apuzzo met with another neurologist, Dr. Vukic, who ordered a series of examinations. Id. After this series of examinations in February of 2017, Dr. Vukic “maintained” the CIDP diagnosis. Id. On August 22, 2017, Ms. Apuzzo saw a different neurologist, Dr. Ma, who determined that her symptoms might be associated with either CIDP, Sjögren's Syndrome, or hypothyroidism. Id. at *7.

From September 22 to 25 to October 2 to 8, 2017, Ms. Apuzzo twice visited a hospital for worsening weakness, fatigue, and shortness of breath. Id.

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